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Title:The Effect of ZEITINY IN TOPICAL APPLICATION Summary:ZEITIN is a plant that has been listed in almost all holy books, has existed for thousands of years, has been a symbol of the Mediterranean countries and civilization. The bioactive compounds found in the structure of the olive oil, an important product obtained from the olive tree, have antioxidant, antimicrobial, anti-inflammatory and anti-carcinogenic effects on the body. It is indicated that when applied topically, it prevents fractures in the chest, reduces the pain, relieves the symptoms of chronic skin damage, prevents the formation of pressure wounds, prevents mouth drying and transcutanous fluid loss, provides skin hydration, protects the skin against pathogenic microorganisms with its antioxidant properties and has positive effects on the healing of the wound. Keywords: Olive Oil, Topical Application, Biological Activity Supporting Institutions: Source: Aguilar Cordero MJ, Villar NM, Barrillao R & et al. 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