Abstract:

Purpose: Acrocordans are the frequently found benign tumors of the skin. In the examination of the anal area, perianal acrocordans are frequently observed. An abnormal lipid and glucose metabolism may play a role in the development of acrocordans. The association of perianal acrocordons with insulin resistance is unknown. The aim of this study is to explore the relationship between perianal acrocordans and insulin resistance. Materials and Methods: The study included 21 phenomena and 21 controls similar to age, gender and body mass index (VKI). The cases of serum hunger glucose, total cholesterol, low-dancy lipoprotein (LDL) cholesterol, high-dancy lipoprotein (HDL) cholesterol and triglyceride (TG) levels were measured. The insulin resistance was calculated by the homeostasis model insulin resistance measurement model (HOMA-IR). The level of HOMA-IR above 2.5 was considered to be insulin resistance.    Results: There is no statistically significant difference between the total cholesterol, HDL cholesterol, LDL cholesterol and TG levels between those identified and controlled. The average HOMA-IR significantly high (p=0,007) was found in the perianal acrocordon group of patients. The proportion of patients with insulin resistance was significantly higher than controlled in patients with perianal acrocordans (p=0,022). The conclusion: Despite the indication that acrocordons are closely related to insulin resistance, there is no study in literature that anal acrocordons are evaluated. The study shows the relationship of perianal acrocordans with insulin resistance.

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