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İlk defa 2019 Aralık ayında Çin’in Wuhan şehrinde görülen ve kısa sürede bir salgına neden olan COVID-19 11 Mart 2020'de Dünya Sağlık Örgütü (WHO) tarafından küresel salgın olarak ilan edilmiştir. Hastalık özellikle bağışıklık sistemi problemleri başta olmak üzere diyabet, kalp hastalıkları gibi diğer kronik hastalıkları olan kişilerde ciddi bir klinik seyir göstermektedir. Virüslere karşı savunmada immün sistemin fonksiyonları ve modülasyonu son derece önemlidir. Birçok araştırmanın sonuçlarına göre, doğal immün sistemi güçlendirmenin yollarından biri de bağırsak mikrobiyotasını dengelemektir. Son zamanlarda yapılan çalışmalar akciğer mikrobiyotası ile bağırsak mikrobiyotasının ilişkili olduğunu ve mikrobiyota dengesinin viral solunum yolu hastalıklarının önlenmesi ve savunmasında önemli olabileceğini göstermektedir. COVID-19’a karşı etkin bir tedavi ve aşı geliştirmek için tüm Dünya’da bilim adamları yoğun olarak çalışmaktadır, ancak henüz kesin tedavisi ya da aşısı bulunamamıştır. Covid-19 hastalığı sürecinde fonksiyonel tıp bakış açısıyla fizyopatolojik mekanizmalara yönelik geliştirilecek yeni profilaktik yaklaşımlar ve tedavi protokollerine ihtiyaç vardır. Bağırsak ve akciğer mikrobiyotaların düzenlenmesinin immün sistemi güçlendirerek korunmada önemli olabileceği, yanı sıra tedavi protokollerinde bir tedavi hedefi olarak yer alabileceğini ileri sürülmektedir. COVID-19 salgını, sağlıklı yaşam, sağlığın korunması, güçlendirme ve bağışıklık sistemi modülasyonu gibi profilaktik yaklaşımların önemini bir kez daha göstermiştir. Mikrobiyota kaynaklarının nasıl elde edilip kullanılacağı, mikrobiyota düzenleyici-destekleyici ürünlerin uygulamasının standardizasyonu ve beslenmenin düzenlenmesinin tedavideki rolü gibi pek çok konuda ileri araştırmalara ihtiyaç vardır.
COVID-19 was first seen in the Chinese city of Wuhan in December 2019 and soon caused a epidemic, which was declared a global epidemic by the World Health Organization (WHO) on March 11, 2020. The disease shows a serious clinical passage in people with other chronic diseases such as diabetes, heart disease, especially immune system problems. The function and modulation of the immune system in the defense against viruses is extremely important. According to the results of many research, one of the ways to strengthen the natural immune system is to balance the intestinal microbiosis. Recent studies show that liver microbiotics are associated with intestinal microbiotics and that the microbiotic balance can be important in the prevention and defense of viral respiratory diseases. Scientists around the world are working hard to develop an effective treatment and vaccine against COVID-19, but the exact treatment or vaccine has not yet been found. In the course of Covid-19 disease, new preventive approaches and treatment protocols are needed to be developed towards physiopathological mechanisms from a functional medical point of view. It is said that the regulation of intestinal and lung microbiots can be important in the protection by strengthening the immune system, as well as that it can be included as a treatment target in the treatment protocols. COVID-19 has once again demonstrated the importance of preventive approaches such as epidemic, healthy life, preservation of health, strengthening and immunity modulation. Advanced research is needed on many topics, such as how microbiological resources are obtained and used, standardization of the application of microbiological regulatory-supporting products and the role of nutrition regulation in treatment.
COVID-19 initially seen in Wuhan China in December 2019 became an epidemic very rapidly and was declared as a pandemic by the World Health Organization (WHO) on March 11, 2020. The disease presents as a serious clinical course in people with other chronic diseases such as diabetes, heart diseases, especially immune system problems. Functions and modulation of the immune system are extremely important in defense against viruses. According to the results of multiple types of research, one of the methods to boost the innate immune system is to balance gut microbiota. Recent studies have shown that lung microbiota and gut microbiota are interrelated and microbiota balance may be important in the prevention of and defense against viral airway diseases. Scientists make great effort worldwide to develop an effective treatment or vaccine against COVID-19, but no cure or vaccine for COVID-19 has been found yet. For COVID-19 disease innovative prophylactic approaches and treatment protocols based on functional medicine perspective and directed towards pathophysiological mechanisms are needed. It’s assumed that regulation of gut and lung microbiota may be important in the prevention of the disease by boosting the immune system and also may be included in treatment protocols as a therapeutic target. COVID-19 pandemic has shown once more the importance of preventive approaches like wellness, maintenance of healthy living, immune system boosting, and modulation. Further advanced researches are needed on subjects such as provision and use of microbiota sources, standardization of administration of microbiota regulating-supplementing products, and role of diet regulation in the treatment.
Field : Sağlık Bilimleri
Journal Type : Uluslararası
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