Abstract:

Introduction: The number of childhood attempts and the related deaths are increasing on a daily basis. Although this situation is a problem for the entire population, it is a more serious problem for those with psychiatric disease. Previous studies have shown the association of inflammation with psychiatric disease. We also planned to investigate the relationship between C-reactive protein (CRP), which is an inflammatory biomarker, with childhood self-determination initiatives. Methods: This research was carried out with a working group and a control group consisting of healthy volunteer individuals who apply for child emergency service from 01.03.2016 to 01.03.2019 due to the initiative of self-determination and who agreed to participate in the work and this research was designed as a factual-control work in advance character. CRP levels have been studied in addition to the demographic and clinical data of both groups. All of these parameters are compared. Results: The study included a total of 239 facts, including 108 facts, 131 controls. There is no difference in demographic data between the groups. When groups were evaluated in terms of serum CRP levels, the average of the control group was estimated at 1.5 ± 1.5 mg/L, while the average of the incident group was estimated at 12.7 ± 6.4 mg/L. (p<0,01) When evaluated in terms of the presence of psychiatric disease, the CRP level was estimated at an average of 14.3 ± 4.2 mg/L for the diagnosed psychiatric disease group, while 9.7 ± 2.7 mg/L for the non-diagnosed psychiatric disease group (p= 0.03). The result: CRP, which is a strong inflammatory indicator in individuals who are in self-sufficiency, is high compared to the normal population. The role of inflammation in this clinical process should be studied in more detail.

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