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KATARAKT CERRAHİSİ GEÇİRMİŞ OLAN HASTALARDA GÖZYAŞI OSMOLARİTESİ VE MEİBOGRAFİNİN DEĞERLENDİRİLMESİ Evaluation of Tear Osmolarity and Meibography in Patients Having Cataract Surgery
2021
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ÖZET Amaç: Bu çalışmanın amacı katarakt cerrahisi geçirmiş olan hastaların oküler yüzeylerini, gözyaşı osmolaritelerini ve kuru göz parametrelerini değerlendirmektir. Gereç ve Yöntemler: Bu prospektif çalışmada kliniğimizde komplikasyonsuz fakoemülsifikasyon cerrahisi geçiren 80 hasta ve 40 kontrol olgusu değerlendirildi. Olguların gözyaşı kırılma zamanı (GYKZ), Schirmer testleri ve meibografi ölçümlerini içeren detaylı göz muayeneleri yapıldı ve osmolarite cihazı (TearLab Corporation) ile ölçülen gözyaşı osmolariteleri kaydedildi. Katılımcılar oküler yüzey hastalık indeksi (OSDI) anketini tamamladılar. Ölçümler kontrol grubu hastalarında 1 kez değerlendirilirken, çalışma grubu hastaları ameliyat öncesi ve ameliyattan 1 ay sonra olmak üzere 2 kez değerlendirildi. Bulgular: Çalışma grubundaki hastaların ( 44 erkek, 36 kadın) ortalama yaşı 69,5 ± 8,9 yıl iken, kontrol grubunun( 21 erkek, 19 kadın) ortalama yaşı 70,4 ± 9,3 yıl idi (p > 0,05). Osmolarite skoru çalışma grubunda ameliyat öncesi ve sonrası sırasıyla 301,5 ± 7,1 mOsm / L ve 309,6 ± 7,4 mOsm / L iken kontrol grubunda 300,9 ± 8,3 m Osm / L olarak bulundu (ameliyat sonrası ile kontrol grubu kıyaslanmasında p = 0,008). Çalışma grubunda ortalama GYKZ’ının ameliyat öncesi 11,9 ± 2,1 sn’den ameliyat sonrası 7,5 ± 3,9 sn’ye düştüğü görüldü (p = 0,016). Ameliyat sonrası GYKZ değeri ile kontrol grubunun GYKZ değeri (12,3 ± 2,2 sn) arasındaki fark anlamlı idi (p = 0,011). Çalışma grubunun ameliyat sonrasında OSDİ skoru anlamlı derecede artarken (p = 0,009), Schirmer test skorunun anlamlı değişim göstermediği görüldü (p > 0,05). Sonuç: Katarakt cerrahisi kuru göz hastalığına ve gözyaşı osmolaritesinde artışa neden olmaktadır. Anahtar Kelimeler: Gözyaşı Osmolaritesi Katarakt Cerrahisi Kuru Göz ABSTRACT Objective: To evaluate the ocular surface, tear osmolarity and dry eye parameters in patients having cataract surgery. Material and Methods: In this prospective study, 80 patients that underwent uncomplicated phacoemulsification surgery in our clinic and 40 control cases were evaluated. Detailed ophthalmological examinations including tear break-up time(TBUT), Schirmer test and meibography measurements were performed and tear osmolarity (TearLab Corporation) values were recorded. All subjects underwent lower and upper lid meibography and meibomian gland loss rates were measured manually. Participants completed the ocular surface disease index (OSDI) questionnaire. Measurements were performed once in the control group, whereas twice (before and one month after surgery) in the study group. Results: The mean age of patients in the study group (44 males, 36 females) was 69.5±8.9 years, while the mean age of the control group (21 males, 19 females) was 70.4±9.3 years (p > 0.05). Osmolarity score was 301.5±7.1 mOsm/L before surgery and 309.6±7.4 mOsm / L after surgery, whereas 300.9±8.3 mOsm/L in the control group (postoperative value of the study group vs control group p=0.008). The mean TBUT was decreased from 11.9±2.1 sec preoperatively to 7.5±3.9 sec postoperatively in the study group (p=0.016) and the difference between postoperative TBUT value and TBUT value of the control group (12 .3±2.2 sec) was significant (p=0.011). OSDI scores significantly increased (p=0.009) whereas Schirmer test scores did not change significantly after surgery (p> 0.05). Conclusion: Cataract surgery causes dry eye disease and leads to an increment in the tear osmolarity. Keywords: Tear Osmolarity Cataract Surgery Dry Eye

Anahtar Kelimeler:

KATARAKT CERRAHİSİ GEÇİRMİŞ OLAN HASTALARDA GÖZYAŞI OSMOLARİTESİ VE MEİBOGRAFİNİN DEĞERLENDİRİLMESİ Evaluation of Tear Osmolarity and Meibography in Patients Having Cataract Surgery
2021
Yazar:  
Özet:

The purpose of this study is to evaluate the ocular surfaces of patients who have undergone cataract surgery, tear osmolarity and dry eye parameters. Tools and Methods: In this prospective study, 80 patients and 40 control phenomena were assessed in our clinic who suffered complications-free fakoemulsification surgery. Detailed eye examinations, including the time of tears break (GYKZ), Schirmer tests and meibographic measurements, and tears osmolarities, measured by the osmolarity device (TearLab Corporation), were recorded. The participants completed the survey of the Oculus Surface Disease Index (OSDI). The measurements were assessed 1 times in the control group patients, while the working group patients were assessed 2 times, prior to the surgery and 1 month after the surgery. Results: The average age of patients in the study group (44 men, 36 women) was 69.5 ± 8.9 years, while the average age of the control group (21 men, 19 women) was 70.4 ± 9.3 years (p > 0.05). The osmolarity score was found in the study group before and after surgery at 301,5 ± 7,1 mOsm / L and 309,6 ± 7,4 mOsm / L respectively, while in the control group at 300,9 ± 8,3 m Osm / L (in comparison with the control group after surgery; p = 0,008). The study group found that the average GYKZ fell from 11.9 ± 2.1 s before surgery to 7.5 ± 3.9 s after surgery (p = 0.016). The difference between the postoperative GYKZ value and the control group’s GYKZ value (12.3 ± 2.2 s) was significant (p = 0.011). The study group found that the OSDI score after the surgery increased significantly (p = 0,009), while the Schirmer test score did not show any significant change (p > 0,05). The result: Cataract surgery causes dry eye disease and increased osmolarity of tears. ABSTRACT Objective: To evaluate the ocular surface, tear osmolarity and dry eye parameters in patients having cataract surgery. Material and Methods: In this prospective study, 80 patients who underwent uncomplicated phacoemulsification surgery in our clinic and 40 control cases were evaluated. Detailed ophthalmological examinations including tear break-up time(TBUT), Schirmer test and meibography measurements were performed and tear osmolarity (TearLab Corporation) values were recorded. All subjects underwent lower and upper led meibography and meibomian gland loss rates were measured manually. Participants completed the ocular surface disease index (OSDI) questionnaire. Measurements were performed once in the control group, whereas twice (before and one month after surgery) in the study group. Results: The average age of patients in the study group (44 males, 36 females) was 69.5±8.9 years, while the average age of the control group (21 males, 19 females) was 70.4±9.3 years (p > 0.05). Osmolarity score was 301.5±7.1 mOsm/L before surgery and 309.6±7. 4 mOsm/L after surgery, whereas 300.9±8.3 mOsm/L in the control group (postoperative value of the study group vs control group; p=0.008). The average TBUT was decreased from 11.9±2.1 sec preoperatively to 7.5±3.9 sec postoperatively in the study group (p=0.016) and the difference between postoperative TBUT value and TBUT value of the control group (12 .3±2.2 sec) was significant (p=0.011). OSDI scores significantly increased (p=0.009) whereas Schirmer test scores did not change significantly after surgery (p> 0.05). Conclusion: Cataract surgery causes dry eye disease and leads to an increase in the tear osmolarity. Keywords: Tear Osmolarity; Cataract Surgery; Dry Eye

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2021
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Alan :   Sağlık Bilimleri

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