Özet:

In this study in dogs diagnosed paroviral enteritis; determining the concentrations of serum iron, total iron bonding capacity (TDBK) and albumin and the relationship of these parameters with the concentrations of serum C-reactive protein (CRP), the major acute phase protein of dogs, was aimed at investigating the effectiveness of predicing systemic inflammation in dogs with paroviral enteritis. The study was conducted on 18 dogs diagnosed with parvoviral enteritis (PVE) and clinically healthy 16 dogs (Control). Serum CRP concentration was significantly higher (P<0.001) in the PVE group (18.50 ± 7.50 mg/dL) compared to the control group (0.50 ± 0.14 mg/dL). There is no significant difference between the two groups (P=0.210) in terms of serum TDBK, while serum iron (P<0. The concentrations of the album (P=0.005) and 001 were found to be significantly decreased according to the control group in PVE group. The concentrations of serum iron (AUC: 0.979, P<0.001) and ≤3.4 g/dL (AUC= 0.785, P=0.005) in parvoviral enteritis dogs were found to have a diagnostic value in the systemic inflammation forecast. The total number of leukocytes, which was ≤5.5x103/μL, was also shown to have a diagnostic value in the prediction of systemic inflammation (AUC: 0.920, P<0.001). Serum TDBK was not statistically meaningful in the prediction of systemic inflammation (P=0.512). As a result, it is found that serum iron has a good correlation with CRP in dogs with parvoviral enteritis and that serum iron can be a sensitive indicator in the assessment of systemic inflammation when used with CRP and total leukocytes.

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