Özet:

Angiotensin converting enzyme 2 (ACE2) receptors, to which the SARS-CoV-2 virus attaches with the spike protein, are abundant in pancreatic endocrine islets and act as the entry point for SARS-CoV-2. It is thought that SARS-CoV-2 causes beta cell damage directly with its entry into pancreatic islet cells and angiotensin-2, which increases as a result of down-regulation of ACE2 following the entry of the virus into the cell, reduces insulin secretion. In this article, the association of newly diagnosed diabetes mellitus and COVID-19 presenting with ketoacidosis, without previous diagnosis of diabetes and steroid use, is presented.