Özet:

Purpose: Multi-primary tumors are tumors that develop simultaneously or at different times in the same or different organs. They are divided into two groups as synchronous and metacronous tumors. Genetic instability, genetic mutation, immune insufficiency, chemotherapy, radiotherapy and target therapies and extension of life are among the causes that increase the development of the second primary tumor. In our study, we intended to present the symptoms of CPT associated with gastrointestinal system (GIS) tumors along with their clinic pathological characteristics. Method: Our study included facts carrying the CPT criteria from the primary tumor diagnosis discussed in our hospital’s GIS councils between 2014-2019. Results: CPT identified 162 cases (4.7%) were identified. 52 of the cases were synchronic and 110 were metacronic tumor groups. Most of the incidents in both groups were male (59.9%). The most frequently observed multi-primary tumor group in men was the left colon-prostat and rectum-right colon, while in women the abdominal and left colon-right colon. The second primary tumors accompanied by GIS tumors in the synchronous and metacronic tumor group belonged to the GIS and urogenital system. The survival rates were found lower in metacronic tumor cases than in synchronic tumor cases, but the difference between them was not statistically meaningful. The survival rate of malignity in the stomach causes was lower compared to the other malignity events and was statistically meaningful. In terms of GIS tumors, prostate and colon in men and breast tumors in women can be a risk factor for the development of CTP.

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