Özet:

Primary infections caused by rubella and cytomegalovirus (CMV) can lead to serious complications due to their potentially teratogenic effects during pregnancy. Rubella and CMV screening of pregnant females is not routinely carried out in Turkey. The purpose of this study was to determine the prevalence of rubella and cytomegalovirus in Izmir among pregnant and antenatal females, and to review seroprevalences reported from different regions of Turkey. Between January 2011 and December 2015, we retrospectively evaluated anti-rubella antibodies and anti-CMV antibodies of pregnant and antenatal females. Females aged 18-45 years were included in the study. Rubella and CMV IgM and G antibodies were tested using the IMMULITE® 2000XPi İmmunoassay System. Rubella IgG and rubella IgM seropositivity were detected in 16,255 (96.5%) of 16,845 and in 206 (1.1%) of the 18,720 pregnant and antenatal females, respectively. Positivity for the anti-CMV IgG and anti-CMV IgM antibody were found in 11,950 (98.7%) and 40 (0.3%) of 13,412 females. In conclusion, this study showed that in our province, a high percentage of pregnant and antenatal females had been exposed to rubella and CMV prior to reaching a child-bearing age. Rubella and CMV seroprevalences show a relatively homogeneous distribution throughout Turkey.

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