Özet:

Nutritional and/or nutritional interactions with medication can often be seen in the treatment practices and can negatively affect the patient’s treatment results. As a result of the interaction, the pharmacokinetic and/or pharmacodynamic effect of the drug may be altered, and the expected effect from the nutritional subject may not be obtained. Drugs can affect the absorption, metabolism, distribution and discharge of foods, disrupting the patient's nutritional status. Also, nutrients and nutrients can also change the absorption and effectiveness of the drug. Because foods and enteral products can significantly reduce the absorption of medications, some medications need to be taken on an empty stomach. Changes in the biological use of medications may result in failure in treatment. In patients receiving enteral nutrition support, the same enteral pathway is usually used for the application of nutritional products and medications. Treatment of medications during the application from the dietary tube and appropriate technical use can also be prevented from risks such as tube lock, reduced drug effectiveness and increased drug toxicity. When medications are intherally applied, the anotomic position of the dietary tube and the width of the tube diameter must also be taken into account. Drugs should never be added directly to the intheral nutrition formula. The mix of medications to be applied from the dietary tube is not recommended due to the risk of physical and chemical intolerance. In addition to pharmacokinetic and pharmacodynamic interactions, the direct physical contact of the drug molecules and nutrients in the carrier systems (such as infusion pipes or bags) or during filling processes is considered an interaction outside the body. This interaction can lead to inability and stability problems that are common in parenteral drugs. Parenteral nutritional solutions should not be used as a drug carrier system due to the complexity of the physical and chemical structure. In the case of intolerance, parenteral nutrition should be avoided from the combination or mix of medications. The risk and importance of food/food-drug interaction will be understood by the clinics and will be possible to prevent unwanted conditions that may arise as a result of increasing their knowledge.

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