Özet:

Hyponatremia, which occurs as a result of the use of selective serotonin reuptake inhibitors (SSRI), which comes to mind first and is thought to be innocent in the treatment of depression; It can cause serious morbidity and mortality. One week after the initiation of fluoxetine treatment with a diagnosis of depression, a 77-year-old female patient admitted to the emergency department with complaints of nausea, vomiting and altered consciousness, and she was followed up in the internal medicine clinic after she had hyponatremia in the analyzes. The medications that the patient was using were discontinued and supportive treatment was initiated with frequent electrolyte monitoring. The causes of hyponatremia in the patient, who had no history of systemic disease other than hypertension and whose sodium level did not increase enough despite drug discontinuation and electrolyte replacement, were investigated in detail. Fluid restriction was applied in the patient considering syndrome of inappropriate secretion of antidiuretic hormone (SIADH) due to fluoxetine from the SSRI group. As a result, after a serious improvement in both clinical and laboratory findings of the patient, she was discharged to come to the psychiatry outpatient clinic. In patients in whom SSRI treatment is initiated; accompanying diseases should be considered before starting treatment and attention should be paid in terms of possible side effects.

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