Özet:

Although reproductive and metabolic disorders associated with polycystic over syndrome are clearly known, the mechanisms between these disorders are still unclear. One of the hypotheses suggested for these mechanisms is related to the circadian rhythm. So far, many reproductive and metabolic disorders have been associated with circadian rhythm disorder. The relationship between melatonin rhythm and metabolic disorders that last until late in the morning and begin early in the night, in women with polycystic over syndrome, has been revealed in recent studies. When the relationship between obesity and melatonin is studied, it is clear that the effect of melatonin is shown by energy consumption rather than energy consumption. This hormone affects energy consumption through adipogenesis, thermogenesis, mitochondrial functions and adipositokin release and shows anti-obesity activity. This summary is believed to keep light on further studies on the therapeutic use of melatonin in obesity associated with polycystic over syndrome and will contribute to the development of strategies for the prevention of obesity.

Anahtar Kelimeler: