Urinary tract infection (UTI) is a common problem encountered in children as well as adults.Sometimes empirical antibiotic treatment might be used depending upon the clinical diagnosis. Theaim of the study was to investigate the common etiologic microorganisms causing UTI and theirantimicrobial sensitivities in children. Urine samples of 1361 children who were evaluated clinically asUTI in Moris Şinasi Pediatric Hospital between January 1998 and December 2002 were investigated.Bacterial growth was noted in 29.9% of the urine samples when the sensitivities of the isolated 407strains to antimicrobials were investigated by standard methods. The isolated bacteria were asfollows: 267 (65.6%) E. coli, 40 (9.8%) Klebsiella spp, 37 (9.0%) Proteus spp, 34 (8.3%), other Gramnegative bacteria and Gram positive bacteria 30 (7.3%). Resistance rates to Ampicillin (AMP),Amoxillin-Clavulonat (AMC), Cefuroxim (CXM), Ceftriakson (CRO), Trimethoprim-Sulfometaxazol(TMP-SXT), Gentamicin (GN) and Amikacin (AK) were found as 73.7 %, 37.1 %, 17.7 %, 0.0 %, 48.8%, 14.3 % and 0.0 %, respectively. Second generation cephalosporins and beta-lactamase resistantpenicillins were found to be effective and they may be the drugs of first choice in the empiricaltreatment of childhood UTI. Amino glycosides may be an alternative in resistant cases.
Urinary tract infection (UTI) is a common problem encountered in children as well as adults.Sometimes empirical antibiotic treatment may be used depending on the clinical diagnosis. The aim of the study was to investigate the common etiological microorganisms causing UTI and theirantimicrobial sensitivities in children. Urine samples of 1361 children who were evaluated clinically asUTI in Moris Shinasi Pediatric Hospital between January 1998 and December 2002 were investigated.Bacterial growth was noted in 29.9% of the urine samples when the sensitivities of the isolated 407strains to antimicrobials were investigated by standard methods. The isolated bacteria were asfollows: 267 (65.6%) E. coli, 40 (9.8%) Klebsiella spp, 37 (9.0%) Proteus spp, 34 (8. 3%), other Gramnegative bacteria and Gram positive bacteria 30 (7.3%). Resistance rates to Ampicillin (AMP),Amoxillin-Clavulonat (AMC),Cefuroxim (CXM),Ceftriakson (CRO),Trimethoprim-Sulfometaxazole(TMP-SXT),Gentamicin (GN) and Amikacin (AK) were found as 73.7%, 37.1%, 17.7%, 0.0%, 48.8%, 14.3% and 0.0%, respectively. Second generation cephalosporins and beta-lactamase resistantpenicillins were found to be effective and they may be the drugs of first choice in the empiricaltreatment of childhood UTI. Amino glycosides may be an alternative in resistant cases.
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
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