Abstract:

Purpose: The two treatment options were planned to be evaluated in terms of clinical and laboratory results by comparing patients with standard heparin and low molecular weight heparin (DMAH) used in their treatments. This retrospective study compared 48 hemodialysis patients using DMAH with 20 patients using standard heparin. Results: The average age of patients was 58.13 ±14.43 years and 48.53 percent were men. The average dialytic period was 5.07±4.01 years and 51.47% of the patients had diabetic nefropathy. Compared to the two groups, age, gender, primary kidney disease, dialytic time, low-intensity lipoprotein, high-intensity lipoprotein, total cholesterol, triglyceride, hemoglobin, ferritin, parathormone, calcium, phosphorus levels, urine reduction rate, Kt/V, erythropoetin and intravenous iron quantity used in treatment, hospitalization and mortality statistically significant differences were not found (P≥0.05). The total iron bonding capacity (P:0.00), serum iron (P:0.01) and potassium (P:0.01) levels in patients using standard heparin were significantly higher than in patients using DMAH, while the transfer saturation (P:0.04) and C-reactive protein (P:0.00) levels were significantly lower. The result: Serum iron and potassium levels in patients using standard heparin were significantly higher, while in patients using DMAH the transferin saturation and serum C-reactive protein levels were significantly higher. There is no statistically significant difference between the two groups in terms of lipid parameters, hemoglobin, dialytic sufficiency indicators and bone mineral parameters.

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