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Abstract Background:The aim of this study was to investigate cardiac complications in patients following lung resections performed in our hospital. The perioperative data of 1186 patients who underwent lung resection between 2017 and 2020 were evaluated retrospectively. Cardiac complications occurred in 136 patients. The relationship between these complications and the patients’ perioperative characteristics was analyzed. Results:There were 287 (81.8%) men and 64 (18.2%) women. The mean age was 58.9 years. Postoperative cardiac complications were significantly more frequent among patients who were older than 65 years (p = 0.001) and male (p = 0.02); had congestive heart failure (CHF) (p < 0.001), coronary artery disease (CAD) (p = 0.003), hypertension (HT) (p = 0.002), hyperlipidemia (HL) (p < 0.001), chronic obstructive pulmonary disease (COPD) (p < 0.001), thyroid disease (p = 0.003), chronic renal failure (CRF) (p = 0.03), cerebrovascular accident (CVA) (p <0.001), or arrhythmia (p < 0.001); underwent surgery due to lung cancer (p = 0.008); received neoadjuvant therapy (p < 0.001); and had ejection fraction (EF) < 60% (p < 0.001). Surgical factors associated with higher rate of PCC were undergoing pneumonectomy (p < 0.001), thoracotomy (p = 0.02), and receiving intraoperative blood transfusion (p < 0.001) or inotropes (p < 0.001). Multiple logistic regression analysis showed that preoperative thyroid disease (p = 0.04), CVA (p = 0.0001), neoadjuvant therapy (p = 0.002), EF < 60% (p = 0.01), pneumonectomy (p = 0.003), intraoperative blood transfusion (p < 0.0001), and high SOFA score (p < 0.0001) were independent risk factors affecting PCC development. Conclusion:Cardiac complications after lung resection were strongly associated with male sex, HT, pneumonectomy, thoracotomy, inotrope use, and neoadjuvant therapy. Keywords: Lung resection, Cardiac complications, Atrial fibrillation, Thoracotomy, Video-assisted thoracoscopic surgery

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