Abstract:

Polyuria is not an uncommon perioperative complication, following coronary artery bypass surgery. Diabetes insipidus (DI) results from inadequate secretion of antidiuretic hormone (ADH) from the pituitary gland (Central DI)or the absence of the normal response by the renal tubules to ADH(Nephrogenic DI).Here we present a 55 years old male who underwent Aortic valve replacement. Postoperatively he developed polyuria and was diagnosed with Diabetes insipidus (DI). Its most likely due toalteration within the left atrial non-osmotic receptor during cardioplegia.It can also be a dysfunction of osmotic receptors in the hypothalamus because of transient cerebral ischemia resultingdue to microthrombi during Cardio-Pulmonary Bypass.The patient recovered from symptoms without any administration of vasopressin.

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