Abstract:

It has become increasingly difficult or sometimes impossible to combat bacterial diseases that were previously easily treated due to the emergence of antibiotic resistance in bacterial fish pathogens. There is therefore an urgent need for more research and the development of eco-friendlier alternatives to antibiotics. One very promising option is the preventive or therapeutic use of strain-specific bacteriophages that target problematic bacterial fish pathogens. In this article, the studies on bacteriophages isolated against bacterial disease agents in aquaculture, especially in our country, have been reviewed. As a result, when we look at the aquaculture sector in our country, detailed studies on phages are needed. To take full advantage of the phage strategy, phage therapy candidates must be carefully selected and characterized in detail to ensure that they are safe to use. One main conclusion is that there is a need for more basic research related to the use of phages in the aquaculture sector of our country. So far, most of the phage studies have been carried out in vitro, and more detailed in vivo studies are needed before the phages can be used in the field.

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