Abstract:

Introduction: Patients undergoing robotic radical prostatectomy RARP who require chronic anticoagulant therapy due to cardiovascular conditions were evaluated for surgical outcomes. Materıal and Methods: In this study, 200 patients who underwent robotic radical prostatectomy with a diagnosis of prostate cancer between 2008 and 2012, were analyzed. In the first group, low molecular weight heparin LMWH was begun to be given to the patients by interrupting their use of oral anticoagulant therapy a week earlier than the surgery. The use of low molecular weight heparin was maintained about a week more after the surgery. The second group included patients who have no history of chronic use of oral anticoagulants therapy. To these patients, low molecular weight heparin as prophylactic was used subcutaneously a day before the surgery and continued until the mobilization. Operative time, blood loss, drain removal time, complication rates, length of hospital stay were compared between two groups.Results: In this study, 24 patients were using oral anticoagulant therapy. Mean operative time was 212,4 min in group 1 and 212,7 min in group 2 p=0.86 . Estimated blood loss was 205 ml and 223 ml in group 1 and 2, respectively p=0.66 . The drain was removed after 2.6 days in group 1 and 2.2 days in group 2. p=0.08 . The length of stay was a mean of 3.8 and 3.2 days in group 1 and 2 respectively p=0.09 . Total complication rate of both groups were 16%. In addition, no statistical difference was observed between minor and major complication rates. Conclusion: Robotic radical prostatectomy can be safely performed in patients who are at the risk of surgery and have been using chronic oral anticoagulant therapy

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