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APENDİKS’İN KARSİNOİD TÜMÖRÜ: 3981 APENDEKTOMİ VAKASININ DEĞERLENDİRİLMESİ Carcinoid Tumor Of Appendix: Evaluatıon of 3981 Appendectomy Cases
2018
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ÖZET Amaç: Bu çalışmanın amacı acil apendektomilerde insidental olarak karşılaştığımız apendiks karsinoid tümörlerinin sıklığı ve tedavi yöntemlerini tartışmaktır. Gereç ve Yöntem: 2008 Eylül – 2016 Eylül tarihleri arasında Erzurum Bölge Eğitim ve araştırma hastanesinde klinik ve radyolojik olarak Akut apandisit tanısı konularak ameliyata alınan ve patolojik sonucu Akut apandisit olarak rapor edilen 3981 hastanın dosyaları elektronik ortamda incelendi. Patolojik olarak Karsinoid tümör tanısı konulan hastalar analize edildi. Bulgular: 2008 Eylül ayı ile 2016 Ağustos ayları arasında ki 8 yıl boyunca toplam 3981 hastaya apendektomi yapıldı ve bu hastaların içerisinde 21(%0.53) hastaya histopatolojik olarak karsinoid tümör tanısı konuldu. Hastaların 11 i erkek 10 u ise kadındı. Hastaların yaş ortalaması 33.7 idi. Ameliyattan önce hiçbir hastaya karsinoid tümör tanısı konulmamıştı ve de spesmenlerin ameliyat sonrası incelenmesi sonucunda tanı konulmuştu. Hastaların tümü acil olarak opere edilmişti. Hastaların hiç birinde karsinoid sendrom bulguları olan diyare ve flushing gibi semptomlar mevcut değildi. Tümör hastaların 18 inde apendixin Uç kısmında, 2 sinde appendixin ortasında ve 1 inde de appendixin taban kısmında idi. Tümör çapı 12 hastada 1 cm den küçük, 5 hastada 1-2 cm arasında ve 4 hastada ise 2 cm den büyüktü. Hastaların 4 üne ikinci bir operasyon gerekmişti ve sağ hemikolektomi yapılmıştı. Sağ hemikolektomi yapılan hastaların tümör çapı 2 cm den büyüktü ve hiç birinde uzak metastaz tespit edilmemişti. Sonuç: Karsinoid tümörler apendiksinsık görülen tümörüdür. Karsinoid tümörler insidental olarak tespit edildiğinden dolayı patoloji sonuçları çok iyi takip edilmelidir. Çapı 1 cm den küçük olan tümörlerde apendektomi, 1-2 cm olan tümörlerde; tümör apendixin kökünde değil ve mezoapendix invazyonu yoksa apendektomi, varsa sağ hemikolektomi, 2 cm den büyük olan tümörlerde ise sağ hemikolektomi yapılmalıdır. Anahtar Sözcu¨kler: Apendix; Karsinoid tümör; Hemikolektomi ABSTRACT Objective: The aim of this study is to discuss the frequency and treatment methods of appendicitis carcinoid tumors that we encounter incidentally in emergency appendectomies. Material and Methods: The files of 3981 patients who were diagnosed as acute appendicitis clinically and radiologically and reported as acute appendicitis as a result of pathology in Erzurum Region Education and Research Hospital between September 2008- September 2016 were rewieved electronically. Patients diagnosed with carcinoid tumor were pathologically analyzed. Findings: A total of 3981 patients underwent appendectomy for 8 years between September 2008 and August 2016 and these patients, 21 (0.53%) were histopathologically diagnosed as carcinoid tumors. 11 of the patients were male and 10 of the patients were female. The mean age of the patients was 33.7. Before the operation, none of the patients had carcinoid tumor diagnosis and the diagnosis was made as a result of examination of the specimens after the operation. All of the patients were operated immediately. Symptoms such as diarrhea and flushing were not present in any of the patients with carcinoid syndrome findings. The tumor was located at the tip of the appendix of 18 patients, in the middle of the appendix of 2 patients and at the base of the appendix of 1 patient. Tumor diameter was smaller than 1 cm in 12 patients, 1-2 cm in 5 patients, and larger than 2 cm in 4 patients. A second operation was required for 4 patients and right hemicolectomy was performed. Patients who underwent right hemicolectomy had a tumor size larger than 2 cm in diameter and no distant metastases were identified. Discussion: Carcinoid tumors are the most common tumor of appendix. Since carcinoid tumors are incidentally identified, the pathology results should be followed very carefully. Appendectomy in tumors smaller than 1 cm in diameter, in 1-2 cm tumors; appendectomy should be performed if the tumor is not at the root of the appendix and if there is no mezoappendix invasion but if there is, right hemicolectomy should be performed in tumors larger than 2 cm in diameter. Keywords: Appendix; Carcinoid tumor; Hemicolectomy

Anahtar Kelimeler:

Carcinoid tumor of Appendix: Evaluation of 3981 Appendectomy Cases
2018
Yazar:  
Özet:

The purpose of this study is to discuss the frequency and methods of treatment of apendic carcinogenic tumors that we accidentally encounter in emergency apendectomies. Tools and Methods: From September 2008 to September 2016 in the Erzurum District Education and Research Hospital, the files of 3981 patients who were diagnosed acute apandicitis clinically and radiologically and as a pathological result acute apandicitis were examined in electronic media. Patients diagnosed with carcinogenic tumors were analyzed. Results: Between September 2008 and August 2016 a total of 3981 patients were diagnosed with apendectomy over the course of 8 years, and 21(0.53) of these patients were diagnosed with histopathological carcinogenic tumors. 11 of the patients were male and 10 female. The average age of patients was 33.7 years. No patient was diagnosed with carcinoid tumor before the surgery and was diagnosed as a result of a post-operative examination of the sperm. All of the patients were operated urgently. No patient was present with symptoms such as diarrhea and flushing, with signs of carcinoid syndrome. In 18 tumor patients, apendixin was in the end part, 2 in the middle of the appendixin and 1 in the base part of the appendixin. The tumor diameter was less than 1 cm in 12 patients, between 1-2 cm in 5 patients and 2 cm in 4 patients. Four patients needed a second surgery and the right hemicolectomy was performed. The tumor diameter of the right hemicolectomy patients was more than 2 cm and no distant metastasis was detected in any of them. The result: Carcinohydroma tumors are a tumor that is seen as apendixinic. Because carcinohydroma tumors are identified accidentally, the pathological results should be very well monitored. In tumors with a diameter of less than 1 cm, apendectomy, in tumors with a diameter of 1-2 cm; tumor is not in the root of apendixin and if there is no mezoapendix invasion, apendectomy, if there is right hemicolectomy, and in tumors with a size of 2 cm, right hemicolectomy should be performed. The aim of this study is to discuss the frequency and treatment methods of appendicitis carcinoid tumors that we encounter incidentally in emergency appendectomies. Material and Methods: The files of 3981 patients who were diagnosed as acute appendicitis clinically and radiologically and as acute appendicitis as a result of pathology in Erzurum Region Education and Research Hospital between September 2008- September 2016 were rewieved electronically. Patients diagnosed with carcinoid tumor were pathologically analyzed. Findings: A total of 3981 patients underwent appendectomy for 8 years between September 2008 and August 2016 and these patients, 21 (0.53%) were histopathologically diagnosed as carcinoid tumors. 11 of the patients were male and 10 of the patients were female. The average age of the patients was 33.7. Before the operation, none of the patients had carcinoid tumor diagnosis and the diagnosis was made as a result of examination of the specimens after the operation. All the patients were operated immediately. Symptoms such as diarrhea and flushing were not present in any of the patients with carcinoid syndrome findings. The tumor was located at the type of the appendix of 18 patients, in the middle of the appendix of 2 patients and at the base of the appendix of 1 patient. The tumor diameter was smaller than 1 cm in 12 patients, 1-2 cm in 5 patients, and larger than 2 cm in 4 patients. A second operation was required for 4 patients and right hemicolectomy was performed. Patients who underwent right hemicolectomy had a tumor you larger than 2 cm in diameter and no distant metastases were identified. Carcinoid tumors are the most common tumor of the appendix. Since carcinoid tumors are incidentally identified, the pathology results should be followed very carefully. Appendectomy in tumors smaller than 1 cm in diameter, in 1-2 cm tumors; appendectomy should be performed if the tumor is not at the root of the appendix and if there is no mezoappendix invasion but if there is, right hemicolectomy should be performed in tumors larger than 2 cm in diameter. Keywords: Appendix; Carcinoid tumor; Hemicolectomy

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