Özet:

Purpose: In children congenital kidney and urinary canal anomaly (CAKUT) involves structural and functional malformations. These anomalies are malformations that are seen in the pre-born period and are the leading cause of recent period kidney disease in children around the world. In this study, the clinical, demographic and therapeutic characteristics of the cases followed by the diagnosis of CAKUT were assessed.  Tools and Methods: The files of cases that apply to our clinic in the two-year period between March 2017 and February 2019 to the Erzurum Regional Education and Research Hospital and receiving CAKUT diagnosis have been reviewed backward. The file information recorded age, gender, family history, screening studies and the treatments they received.  Results: 378 facts were taken to our study, 179 girls (47 percent). 4), 199 men (52.6%) and an average age of 38 months (minimum 1 month-big 212 months). In our study, 132 of the incidents (35 percent) of ureteropelvial depression, 128 (33.9 percent) of primary vezicoureteral reflux, 34(2.9 percent) of renal agenesis, 19(5.1 percent) of ectopic kidneys, 19(5.1 percent) of double collector system, 16(4.2 percent) of horse kidneys, 15(3.8 percent) of renal hypoplasia, 14(3.8 percent) of polystic kidneys, 13(3.4 percent) of multicistic displastic kidneys, 11(2.9 percent) of ectopel depression, 10(2.7 percent) of ectopel kidneys, 9(2.4 percent) of posterior valetral and 1(0.3 percent) of the epilepsy kidneys, 13(3.2 percent) of the epilepsy kidneys and 13(3.2 percent) of the epilepsy kidneys. In the 43 cases there were a number of CAKUT forms. The case with CAKUT history in the family was identified as 29(7.7 percent). The result: CAKUT can cause serious morbidity throughout life. The careful and regular follow-up of children from the antenatal period is important. Early diagnosis in cases to be treated, while reducing the risk of permanent kidney damage, still plays an important role for CBD in our country.

Anahtar Kelimeler:

Özet:

Aim: Congenital anomalies of the kidney and urinary tract (CAKUT) in children include structural and functional malformations. These anomalies are the most common malformations in the prenatal period and constitute the leading cause of end-stage renal disease in children worldwide. In this study, the clinical, demographic, and treatment characteristics of the children with CAKUT were evaluated.  Material and Methods: We retrospectively reviewed the medical records of the children with CAKUT who were admitted to our outpatient clinic during the two years period at Erzurum Regional Education and Research Hospital. Age, gender, family history, imaging studies and treatments were recorded.  Results: The study included 378 patients. 179(47.4%)  children were female, 199(52.6%) children were males. The mean age was 38 months(min 1 month-max 212 months). In our study, ureteropelvic junction obstruction was detected in 132(35%) patients, primary vesicoureteral reflux was detected in 128(33.9%) patients, renal agenesis was detected in 34(9%) patients, and ectopic kidney was detected in 19(5.1%) patients, double collecting system was detected in 19(5.1%) patients, horseshoe kidney was detected in 16(4.2%) patients, renal hypoplasia was detected in 15(3.8%) patients, polycystic kidney disease was detected in 14(3.8%) patients, multicystic dysplastic kidney was detected in 13(3.4%) patients, uretero-vesical junction obstruction was detected in 11(2.9%) patients, ureterocele was detected in 10(2.7%) patients, posterior urethral valve was detected in 9(2.4%) patients and urethral hypoplasia was detected in one (0.3%) patient. Eighty-seven (22.9%) patients had renal scar and 13(3.4%) patients had chronic kidney disease. Forty-three patients had multiple CAKUT forms. Twenty-nine(7.7%) of the patients had a history of CAKUT in the family..  Conclusion: CAKUT may cause serious morbidity throughout life. Careful and regular monitoring of children from the antenatal period is important. Although early diagnosis reduces the risk of permanent renal damage in cases requiring treatment, it still plays an important role in CKD in our country.