Özet:

Background: Mild cognitive impairment (MCI) is a heterogeneous condition with cognitive characteristics between normal aging and dementia. The present prospective study was conducted to assess clinical presentation of mild cognitive impairment and its outcome in patients presented in psychiatry department of a tertiary care centre.Materials & Methods: The patients for this study were recruited from psychiatry department at S.K. Medical College, Sikar, Rajasthan. The patients were seen by a behavioral neurologist who obtained a medical history from the patient and neurologic examination was also done The first set of tests was used for diagnostic purposes and included the, Wechsler Memory Scale–Revised, Auditory Verbal Learning Test. The second set of tests was used for research purposes and included the Mini-Mental State Examination (MMSE), Dementia Rating Scale (DRS), Boston Naming Test. Diagnoses were made for dementia and AD. The outcome of patients with an MCI using these criteria was noted. Results: We have enrolled 80 subjects with the diagnosis of MCI. A total 0f 200 patients were included in the study as controls and 60 patients were suffering from Alzheimer’s disease. The subjects with MCI were significantly impaired on all memory measures relative to control subjects and appeared similar to the patients with AD. The outcome of the subjects with MCI shows that at initial examination 1OO% patients were with MCI. At 12 months 80% patients were with MCI, at 24 months 70% patients were with MCI, at 36 months 60% patients were with MCI and at 48 months 55% patients were with MCI.Conclusion: The present study concluded that outcome of the subjects with MCI shows that at initial examination 1OO% patients were with MCI and at 48 months 55% patients were with MCI.

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