Özet:

Budd-Chiari Syndrome (BCS) is a disorder resulting from the obstruction of hepatic veins at the level of junction with the vena cava inferior because of the disruption of venous drainage of the liver from various reasons. The etiology rarely involves viral infections. Epstein-Barr virus (EBV) is a virus which may cause multi-systemic clinic disorders. A 29- year-old female with complaints of dizziness, nausea, widespread maculopapular rash in abdominal and dorsal regions was hospitalized. Physical examination revealed fever, cervical bilateral multiple lymphadenopathy (largest was 1x1 cm in size), painful hepatomegaly, splenomegaly and massive ascites. Laboratory results showed hematologic parameters suggesting disseminated intravascular coagulopathy (DIC). Monospot test for EBV was positive and EBV viral capsular antigen (VCA) IgG was found at a titer of 1/320. Portal Doppler ultrasonography revealed hepatic vein thrombosis, splenomegaly, hepatomegaly and hypertrophy of caudate lobe, and the patient was accepted as BCS. The patient was given the diagnosis of vestibular neuritis after neurologic and otologic examination and the biopsy taken from the skin lesions suggested the diagnosis of lichen planus. After review of the literature, it was considered that EBV infection may cause a clinical picture as seen in our case and may result in BCS with its potential to form DIC. In conclusion we found it worthwhile to present our case in regard to EBV's potential to cause a wide clinical spectrum including DİC, vestibular neuritis, lichen planus and finally BCS.

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