Özet:

Micro RNAs and their relation with cancerMicroRNAs (miRNAs) are a class of small non-coding endogen RNA molecules usually 20-23 nucleotidesat length. They have shown to role in many physiological and pathological processes including cellcharacterization and differentiation. Additionally some miRNAs were identified as oncogenes while someothers are tumor-suppressors in cancer. This data indicates their modulatory effects on tumor progression,invasion and metastasis. After the effects of miRNAs on carcinogenesis were discovered, expression levelsof miRNAs on different cancer and normal cell lines were evaluated and differences found between normaland pathological tissues. Comparisons of miRNA expression levels between cancer and normal cells havegained attention on diagnosis, prognosis ant treatment of cancer. With the increasing knowledge aboutmiRNA functions and their roles in cancer, they became a new hope for understanding molecular pathologyof cancer and for developing molecular targeting treatment method

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