Objectives: In this study, we aimed to compare the adequacy of conventional smear (CS) and liquid-based cytology (LBC) methods in thyroid fine-needle aspiration biopsy (FNAB) samples obtained without an accompanying cytopathologist during the procedure. Furthermore, we aimed to investigate the presence of a significant difference between the rates of nodules classified as Bethesda Category III and malignancy in both techniques and the features of the nodules affecting malignancy. Methods: A total of 625 nodules from 572 patients who were found suitable for biopsy were included in this retrospective study. FNABs were performed by interventional radiologists without an accompanying cytopathologist during the procedures. The specimens were either prepared using CS or LBC preparation methods. Cytopathological diagnostic adequacy and cytopathological results of the specimens were evaluated according to Bethesda category, and the relationship between the morphological findings was evaluated retrospectively. Results: Of all the biopsy preparations, 338 (54.1%) of them were transferred to pathology in liquid-based solution and 287 (45.9%) were transferred as CS. Malignancy rates of the biopsy samples were found similar in both LBC and CS methods. Considering the nodules classified as Bethesda Category II, III, IV, V, and VI, there was no statistical difference between the results of both methods. Non-diagnostic biopsy rate was higher in the specimens prepared by CS method (p<0.001). Conclusion: In this study, the adequacy rate of FNAB was found significantly higher in LBC method compared to the CS method. LBC was more practical and faster than the CS method. We think that LBC method may be preferred in FNAB of thyroid nodules.
In this study, we aimed at comparing the adequacy of conventional spread and liquid-based cytology (SBS) methods in thyroid thin injection aspiration biopsy (IAB) samples taken without a sitopathologist accompanied during the process. We also intended to investigate whether the samples obtained by both techniques have a significant difference between the results according to the Bethesda category. A total of 625 nodes of 572 patients suitable for biopsy were included in this retrospective study. IABs were performed by initiative radiologists without a sitopathologist accompanying during the processes. The samples were prepared using either conventional broadcasting or SBS preparation methods. The cytopathological diagnosis adequacy and cytopathological results of the samples were assessed according to the Bethesda category and the relationship between the morphological findings was assessed as retrospective. 338 of all biopsy samples (54.1%) were prepared using the SBS spread method, 287 (45.9%) were prepared as conventional smar. The malignity rates of biopsy samples were found similar in both SBS and conventional spread methods. Considering the nodes classified as categories II, III, IV, V, VI in Bethesda, there was no statistical difference between the results of both methods. The non-diagnostic biopsy rate was higher in samples prepared by conventional spread method (p<0,001). The result: In this study, the IIB qualification rate in the SBS method was significantly high compared to the conventional smear method. SBS was more practical and faster than the conventional transmission method. We think that the SBS method can be preferred in the IAB of the thyroid nodes. (SETB-2021-11-335)
Alan : Sağlık Bilimleri
Dergi Türü : Ulusal
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