Özet:

Objective: In this study we evaluated the optic nerve head (ONH) cupping parameters and thickness of retinal nerve fibre layers (RNFL) with Heidelberg retinal tomography (HRT) and optical coherence tomography (OCT) in patients with the diagnosis of physiological cupping whose intraocular pressure (IOP) and visual fields (VF) are normal but ONH cupping is more than 0.6. We then compared them with early glaucomatous (EG) patients and normal cases as control (NK). Material and Methods: The study enclosed 57 eyes of 57 patients having no previous diagnosis of glaucoma but with physiological cupping C/D≥0.6 on routine ophthalomological evaluation and 56 eyes of 56 early glaucomatous patients followed in our glaucoma unit. Control group (NK) consisted of 55 eyes of 55 cases with C/D≤0.4. All the patients were evaluated with whole ophthalmologic examination, intraocular pressure measurements, with gonioscopy and tests for thickness of central cornea (TCC), OCT, RNFL analyses, HRT, ONH parameters and VF tests. Only one eyes of each patient were randomly chosen. Results: All of the three groups were comparable with regards to TCC and refraction values (p=0.437 and p=0.478). But there was significant differences regarding OCT and HRT evaluations (p<0.001). Disc areas of PC cases were greater than those of other groups (p<0.001). The cupping area of PC cases was similar to those of EG cases (p=0.085) whereas it was significantly greater than those in control group (p<0.001). There was no difference in Rim area of PC and C groups as was expected (p=0.355) and Rim area of both groups was measured thicker than that of EG cases (p=0.002). It was seen that the most important OCT parameter differentiating PC and EG cases from each other was mean RNFL thickness. When the sensitivity and specificity of OCT and HRT measurements in differentiating PC cases were compared it was seen that OCT was superior. Conclusion: Optic coherence tomography and Heidelberg retinal tomography might be valuable in differentiating between large optic nerve head cupping cases from glaucoma.

Anahtar Kelimeler: