Abstract:

Background: Vitamin D has a significant role in the metabolism of calcium and bone. Therefore, its deficiency leads to rickets in growing children and osteomalacia in adults. The classical functions of Vitamin D in bone metabolism and calciumphosphorus homeostasis is well established. The non-classical functions of Vit D as an immunomodulatory and growth-promoting factor influencing the overall well being in general and respiratory health, in particular, is the subject of current interest. It is reported that vitamin D plays a crucial role in foetal lungs proper growth and maturity.In many children with steroid-resistant asthma, vitamin D supplements may increase the responsiveness to steroids. Vitamin D deficiency states were reported to be associated with an increased risk of acute exacerbations of bronchial Asthma. Our study is conducted to determine serum levels of vitamin D in asthmatic children and association of vit D deficiency with asthma.

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