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Amaç: Brusella enfeksiyonu dünya genelindeki en yaygın bakteriyel zoonoz olup ülkemizde de yüksek görülme oranları ile bir halk sağlığı sorunu olmaya devam etmektedir. Biz de çalışmamızda brusellozun ülkemizde sık görüldüğü bölgelerden biri olan Şırnak ilindeki olguları irdeledik. Gereç ve Yöntem: İkinci basamak bir hastanenin enfeksiyon hastalıkları ve klinik mikrobiyoloji polikliğine Ekim 2017- Aralık 2018 tarihleri arasında başvuran, ayaktan ve yatarak takip edilen 83 brusella ile enfekte hastanın olası risk faktörleri, başvuru şikayetleri, şikayetlerin başlama zamanı, klinik bulguları, gelişen komplikasyonları ve başlanan tedavileri retrospektif olarak incelendi. Bulgular: Çalışmaya alınan 83 hastanın %61,4’ü (51/83) kadındı. Hastaların yaş ortalaması 35,3 (15-84) saptandı. Brusella enfeksiyonuna en çok ev hanımlarında rastlandı (%39,7) ve en yaygın risk faktörü taze peynir tüketimi idi (%78,3). En sık görülen semptom ise yaygın kas ve eklem ağrısı idi. İkili ve üçlü kombinasyonlar şeklinde 13 farklı tedavi rejimi uygulandı, hastaların %13,2’sinde çeşitli nedenlerle tedavi değişikliği yapıldı. Brusella ile enfekte hastaların %30,1’inde hepatit, %13,2’sinde kemik eklem tutulumu saptandı. Osteoartiküler tutulumu olanlarda eritrosit sedimantasyon hızı (p=0,009) ve C reaktif protein (p=0,046) yüksekliği, olmayanlara göre istatistiksel olarak anlamlı saptandı. Üç hastada (%3,6) ise epididmoorşit gelişmişti. Hastaların %26,5’inde relaps görüldü. Sonuç: Özellikle bölgemiz gibi brusella enfeksiyonunun yaygın olarak görüldüğü yerlerde nonspesifik semptom ve bulgular ile başvuran hastalarda mutlaka brusella enfeksiyonu akılda tutulmalı ve hastalar bruselloz açısından tetkik edilmelidir.
Goal: Brussels infection is a worldwide bacterial zoonosis and continues to be a public health problem with its high prevalence in our country. In our work, we also discussed the events in the province of Sırnak, which is one of the areas where bruselose is frequently seen in our country. Tools and Methods: The potential risk factors, application complaints, time of start of complaints, clinical findings, developing complications and starting treatments of patients infected with 83 brusella followed by foot and bed between October 2017 and December 2018 were examined retrospective. Results: 61.4% of the 83 patients involved were female (51/83) The patient’s average age was 35.3 (15-84) Brusella infection was found in many households (39.7%) and the common risk factor was the consumption of fresh cheese (78.3%) The most common symptom was common muscle and joint pain. 13 different treatments were implemented in the form of double and triple combinations, and 13.2% of patients changed treatment for various reasons. In 30.1 percent of patients infected with Brusella, hepatitis and 13.2 percent of patients with osteoartritis were diagnosed. In those with osteoartic constipation, the rate of erythrosite sedimentation (p=0,009) and the height of C reactive protein (p=0,046) were statistically significant compared to those not. In three patients (3.6 percent) epididmorphitis developed. In 26.5 percent of patients, recurrence was observed. Result: In patients with non-specific symptoms and findings, especially in places where brusella infection is common in our region, brusella infection should be kept in mind and patients should be examined for brusellosis.
Aim: Brucellosis is the most common bacterial zoonosis in all around the world and still a public health threat with high rates of incidence in Turkey. In the present study, we evaluated the brucella infection cases, manifested in Sirnak, one of the regions that brucellosis is common in our country. Materials and Methods: We retrospectively collected data of 83 outpatients and inpatients who admitted infectious disease department of a second-line hospital between dates of October 2017 and December 2018. We have evaluated possible risk factors for brucellosis, complaints of the patients, the initiation time of the complaints, clinical signs, complications and treatment regimes. Results: 61.4% (51/83) of the patients included in the study were female. The mean age of the patients was 35.3 (15-84). Brucella infection was most common among housewives (39.7%) and the most common risk factor was fresh dairy cheese consumption (78.3%). The most common symptom was muscle and joint pain. We have applied 13 different treatment regimens in the form of double and triple drug combinations, and treatment of 13.2% of the patients was switched because of various reasons. 30.1% of the patients infected with brucella had hepatitis and 13.2% had osteoarticular involvement. Erythrocyte sedimentation rate (p = 0.009) and C reactive protein (p = 0.046) were statistically significant high in patients with osteoarticular involvement compared to without. The correlation between higher Erythrocyte sedimentation rate (p = 0.009), C reactive protein (p = 0.046) values and osteoarticular involvement was statistically significant. Epididymoorchitis was developed in three patients (3,6%). The rate of relapse was 26.5%. Conclusion: Brucella infection should be kept in mind in patients presenting with nonspecific symptoms, especially in areas where brucella infection is common like our region and patients should be examined for brucellosis.
Alan : Sağlık Bilimleri
Dergi Türü : Ulusal
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