Özet:

Pectin/p(HEMA-co-AAc)/AgNP nanocomposite hydrogels were developed with a simple, cost-effective and environmentally friendly process. First, pectin/p(HEMA-co-AAc) hydrogels was synthesized with pectin as grafting backbone, 2-hydroxyethyl methacrylate and acrylic acid (HEMA and AAc) monomers, N,N'-methylenebisacrylamide (MBA) crosslinker and ammonium persulfate (APS) - N,N,N',N '-tetramethyl ethylenediamine (TEMED) a redox initiator pair by free radical polymerization. The chemical structure and surface properties of pectin/p(HEMA-co-AAc) hydrogels were elucidated by Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). Next, silver ions were incorporated into the hydrogel matrix and pectin/p(HEMA-co-AAc)/AgNP nanocomposite hydrogel was developed by in situ reduction of silver ions (Ag+) to silver nanoparticles using Parthenocissus Quinquefolia L leaf extract. The size of AgNPs of nanocomposite hydrogels were determined by characterizing with a transmission electron microscope (TEM). Finally, the antimicrobial and antifungal activities of the obtained nanocomposite hydrogels was performed by disk diffusion method using Bacillus Cereus (gram-positive), Escherichia Coli (gram-negative), bacterial species and Candida albicans as fungal species.

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