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Küçük ruminant lentivirusu ile enfekte keçilerin farklı dokularındaki histopatolojik ve immunohistokimyasal bulguları
2023
Journal:  
Eurasian Journal of Veterinary Sciences
Author:  
Abstract:

Amaç: Küçük ruminant lentivirus enfeksiyonu, koyun ve keçilerde patolojik ve klinik olarak mastitis, maedi, visna ve artritise neden olan bir dizi ana hedef organı aynı anda ve immunpatojenik olarak etkileyebilen kronik ve tedavi edilemez bir karaktere sahiptir. Bu çalışmanın amacı, histopatolojik ve immunohistokimyasal olarak enfekte keçilerin farklı dokularındaki lezyonları ve hücresel dağılımını ortaya koymaktır. Gereç ve Yöntem: Çalışmada, seropozitif olduğu bilinen toplam 6 adet keçi, ayrıca 1 adet abort fötus kullanıldı. Histopatolojik bulgular ve immunohistokimyasal olarak, hücresel dağılımlar tespit edildi. Bulgular: Histopatolojik olarak bronkopnömoni ve kronik intersitisyel pnömoni, enteritis, böbreklerde proksimal ve distal tubulus epitellerinde hidropik dejenerasyon ve nekroz, hiyalin damlacıkları ve hiyalin silindirleri, dalakta konjesyon ve lenfoid hücrelerde azalma, kalpte konjesyon, hiyalin dejenerasyonu ve nekroz ile karaciğerde hidropik dejenerasyon, nekroz ve hepatitis gözlendi. İmmunohistokimyasal olarak akciğerde bronş ve bronşiyollerin epitellerinde, alveoler makrofajlarda ve lenfositlerde, dalakta lenfosit ve makrofajlarda, bağırsaklarda kript ve villus epitellerinde, lenfosit ve makrofajlarda, karaciğerde ise Kupffer hücrelerinde ve lenfositlerde pozitif boyanmalar görüldü. Aksine, böbrekler ve kalpte pozitiflik görülmedi. Öneri: Sonuç olarak, keçi yetiştiriciliğinde önemli bir yeri bulunan küçük ruminant lentivirus enfeksiyonunda elde edilen veriler ve bu verilerin, yeni çalışmalarda ve geliştirilebilecek mücadele programlarında önem arz edeceği düşünülmektedir.

Keywords:

Histopathological and immunohistochemical findings in the different tissues of infected cows with small ruminant lentivirus
2023
Author:  
Abstract:

Purpose: Small ruminant lentivirus infection has a chronic and untreatable character that can simultaneously and immunopathogenically affect a series of main target organs that pathologically and clinically cause mastitis, maedi, visna and arthritis in the sheep and goats. The aim of this study is to detect the histopathological and immunohistochemically infected goats’ injuries and cellular distribution in different tissues. In the study, a total of 6 goats known to be seropositive, as well as 1 abortion foetus were used. Histopathological findings and immunohistochemically, cellular distortions were detected. Results: Histopathologically, bronchopneumonia and chronic intersitutional pneumonia, enteritis, hydropic degeneration and necrosis in the proximal and distal tubulus epithels in the kidneys, hyaline drops and hyaline cylinders, wave conjection and reduction in lymphoidal cells, conjection in the heart, hyaline degeneration and necrosis, hydropic degeneration in the liver, necrosis and hepatitis were observed. Immunohistochemically in the lungs bronchial and bronchial epithels, alveol macrophages and lymphocytes, lymphocytes and macrophages in the waves, crypt and villus epithels in the intestines, lymphocytes and macrophages, and in the liver, and in the Copper cells and lymphocytes, positive paintings were observed. On the contrary, no positive reaction was observed in the kidneys and heart. Recommendation: As a result, the data obtained from the small ruminant lentivirus infection, which has an important place in the cattle cultivation, and these data are believed to be important in new studies and combat programs that can be developed.

Keywords:

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Eurasian Journal of Veterinary Sciences

Field :   Sağlık Bilimleri

Journal Type :   Uluslararası

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Eurasian Journal of Veterinary Sciences