Abstract:

Purpose: In our study, the results of blood culture samples sent to our laboratory from 1 March 2019 - 29 February 2020 before pandemic (PÖ) and 1 March 2020 - 1 March 2021 during pandemic (PD) Elâzığ Fethi Sekin City Hospital, Intensive Care Units (YBU) were examined retrospectively. During these periods, our hospital is designed to compare the bacterial sensitivity of the bacterial bacterial bacterial bacterial bacterial bacterial bacterial bacterial bacterial bacterial bacterial bacterial bacterial bacterial bacterial bacterial bacterial bacterial bacterial bacterial bacterial bacterial bacterial. Method: The blood culture bottles coming to our laboratory were traced by the BACTEC 9120 (Becton-Dickinson Diagnostic Instrument Systems, USA) automation system. The "positive warnings" from blood-cultural bottles have been worked with the automated Vitek version 2.0 (BioMérieux, France) for the identification of microorganisms and the detection of antibiotic sensitivities. The colystine resistance is used by the liquid microdilusion method. Results: In the pre-COVID-19 period, a total of 1,374 blood culture samples came to our laboratory and 163 (11.9%) were reproduced. In the PD, there were a total of 847 blood culture examples. Of these, 148 (17.5%) were reproduced. Coagulate negative staphylococcus (KNS) (40.5%) in the first three places in the PÖ, Klebsiella spp. (%13.1), Staphylococcus aureus (%13.5); and in PD the KNS (%50.7), Candida spp.(%10.1), Acinetobacter spp (%9.5) was detected. Two periods between Klebsiella spp, S. The variation in the reproductive rates of aureus, KNS and mayas has been statistically meaningful (p<0.05). In PD, Escherichia coli’s general antibiotic sensitivity has increased and the extended spectrum beta-lactamic positive rate has decreased. by Klebsiella spp.Acinetobacter and spp.In particular, it has been determined that imipenem sensitivity is not statistically meaningful in PD. The result: The extension of the hospitalization period and the high-level steroid use in the treatment of COVID-19 in our hospital has been considered to have increased candidemia in patients with intensive care. Early diagnosis and monitoring of Candida infections will play an important role in reducing deaths from COVID-19 in patients with severe COVID-19 fungal coninfection. Acinetobacter spp and acinetobacter spp. Since the carbpenem resistance is determined to increase in COVID-19 PD, when the carbpenem therapy should be started, the combined therapy options for the carbpenem therapy can be assessed taking into account this situation. The Acinetobacter spp. In the PD, there is no carbon sensitive juice that could be a clonal resistance.

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