In the study, the relationship between unemployment and interest rate with growth in Turkey was examined by taking annual data for 1980-2016 period. In the time series, the unit root test was first applied to the variables and the variables were found to be stationary at the primary level. After cointegration analysis, error correction model and equation were developed by analyzing short term effect of variables. As a result of the analysis; it is seen that there are short- term and long- term relationships among the variables. The Granger causality test revealed that there was a two-way causality between unemployment and GDP, and one-way causality between interest and unemployment. The conclusion that the economic crises that took place in the world and in Turkey and the policies that have been applied during they ears that have been examined, caused structural changes. TheBai- Perron fracture test has identified three structural fracture periods for interest, unemployment and GDP.