Abstract:

Patients diagnosed with type 2 diabetes mellitus (T2DM) with two oral anti-diabetic drugs (OAD=Oral Anti-diabetic Drug) not regulated blood sugar (Hemoglobin A1c=HbA1c=7%-10) and basal-plus insulin treatment were considered retrospective. Of the 78 patients surveyed, 15 patients were found to receive and continue basal-plus treatment. The morning hunger blood sugar values showed that insulin was triggered and triggered at 17:00, and the high postprandical blood sugar values showed that insulin was added and triggered to the evening meal. A significant decline in morning hunger, fatigue, night 23:00 and 02:00 blood sugar, after evening fatigue and night 23:00 blood sugar was observed. HbA1c is 8.3% to 6%. When a significant decline was detected to 8 (p<0.001), no significant changes were detected in hypoglycemia and weight gain. After all, in patients who cannot provide blood sugar regulation with OAD, basal-plus insulin treatment has been found to provide effective blood sugar regulation and HbA1c decrease without increasing side effects. With these results it was found that basal-plus therapy was a suitable step in the transition to intensive insulin therapy.