Objectives: Urinary tract infection in neonatal period is an important cause of late sepsis for term and preterm infants. The aim of this study was to evaluate the results of clinical, laboratory and radiological examinations of patients admitted to the third-level neonatal intensive care unit with urinary tract infection. Materials and Methods: The results of clinical, laboratory and radiological imaging of term newborns who were diagnosed as urinary tract infection according to urine culture obtained by bladder catheterization and accepted into neonatal intensive care unit were obtained from computer records retrospectively. Differences and relationships of the data were statistically evaluated. Results: The data of 43 patients who were followed up in the neonatal intensive care unit with the diagnosis of urinary tract infection between 2015-2018 were evaluated. 77 (n=30) % of the cases were male and the diagnosis day was median 10 (7-28 days). 22 (51%) of the cases presented with jaundice, 6 (13.96%) with vomiting, 5 (11.62%) with fever and 4 (9.30%) with feeding difficulties and 13.96% had no symptoms at admission. The most common microorganisms were Escherichia coli (60.46%) and Klebsiella pneumonia (20.93%). Amikacin resistance was significantly lower in patients with Escherichia coli and Klebsiella pneumonia compared to gentamicin resistance (p<0.001 and p = 0.046). Conclusion: Neonatal urinary tract infections can be clinically asymptomatic or cause sepsis and renal damage and may be a major cause of morbidity and mortality. The initiation of empirical antibiotic therapy according to variable antibiotic resistance is as important as the clinical and laboratory findings for early and effective treatment.
Objectives: Urinary tract infection in the neonatal period is an important cause of late sepsis for term and premature infants. The aim of this study was to evaluate the results of clinical, laboratory and radiological examinations of patients admitted to the third-level neonatal intensive care unit with urinary tract infection. Materials and Methods: The results of clinical, laboratory and radiological imaging of term newborns who were diagnosed as urinary tract infection according to urine culture obtained by bladder catheterization and accepted into neonatal intensive care unit were obtained from computer records retrospectively. Differences and relationships of the data were statistically evaluated. Results: The data of 43 patients who were followed up in the neonatal intensive care unit with the diagnosis of urinary tract infection between 2015-2018 were evaluated. 77 (n=30) % of the cases were male and the diagnosis day was median 10 (7-28 days). 22 (51%) of the cases presented with yellow, 6 (13.96%) with vomiting, 5 (11.62%) with fever and 4 (9.30%) with feeding difficulties and 13.96% had no symptoms at admission. The most common microorganisms were Escherichia coli (60.46%) and Klebsiella pneumonia (20.93%). Amikacin resistance was significantly lower in patients with Escherichia coli and Klebsiella pneumonia compared to gentamicin resistance (p<0.001 and p = 0.046). Conclusion: Neonatal urinary tract infections can be clinically asymptomatic or cause sepsis and renal damage and may be a major cause of morbidity and mortality. The initiation of empirical antibiotic therapy according to variable antibiotic resistance is as important as the clinical and laboratory findings for early and effective treatment.
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
Benzer Makaleler | Yazar | # |
---|
Makale | Yazar | # |
---|