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Prostat kanserinde iğne biyopsi ve radikal prostatektomi örnekleri arasındaki uyum
2020
Journal:  
Acta Oncologica Turcica
Author:  
Abstract:

GİRİŞ ve AMAÇ: Bu çalışmada prostat kanseri nedeniyle radikal prostatektomi uyguladığımız hastalarımızda iğne biyopsisi örnekleri ile radikal prostatektomi örnekleri arasındaki uyumu değerlendirmeyi amaçladık. YÖNTEM ve GEREÇLER: Retrospektif çalışmada, Kasım 2010 – Mayıs 2020 tarihleri arasında prostat kanseri nedeniyle radikal prostatektomi yapılan 167 erkek hasta değerlendirildi. Patolojik tanıları merkezimizde yapılan iğne biyopsisi ile konulan ve radikal prostatektomi öncesi prostat kanserine yönelik herhangi bir tedavi almamış hastalar çalışmaya dahil edildi. İğne biyopsileri dış merkezde yapılan 92 hasta, patolojik tanıları transüretral rezeksiyon materyali ile konulan 2 hasta ve radikal prostatektomi öncesinde hormonoterapi alan 1 hasta ile radyoterapi alan 1 hasta çalışma dışı bırakıldı. BULGULAR: Çalışmaya dahil edilen toplam 71 hastanın yaş ortalaması 62.3 ± 6.0 (aralık, 46 – 75) yıl, tanı öncesi ortalama PSA düzeyi ise 10.0 ± 7.6 (aralık, 3.2 – 48.1) ng/mL idi. 31 (%43.7) hastada parmakla rektal muayenede şüpheli bulgu mevcuttu. İğne biyopsisi örnekleri ile radikal prostatektomi örnekleri arasındaki Gleason skoru, prognostik grup ve tümör lateralitesi açısından uyum sırasıyla %66.2, %59.2 ve %74.6 idi. TARTIŞMA ve SONUÇ: Prostat kanseri tanısı konulan hastalarda iğne biyopsisi örneklerinin patolojik değerlendirmesi tedavi yöntemlerinin belirlenmesinde kritik role sahiptir. Bununla birlikte, iğne biyopsisi örneklerinin prostat patolojisini yüksek bir uyumla öngörmediği akılda tutulmalıdır.

Keywords:

Compatibility Between Injection Biopsy and Radical Prostatectomy Examples
2020
Author:  
Abstract:

Introduction and Purpose: In this study, we aimed at assessing the compatibility between injective biopsy samples and radical prostatectomy samples in our patients we apply radical prostatectomy due to prostate cancer. Method and Requirements: In a retrospective study, 167 male patients with radical prostatectomy due to prostate cancer were evaluated between November 2010 and May 2020. Patients who were placed with injective biopsy in our pathological diagnoses center and who did not receive any treatment for prostate cancer prior to radical prostatectomy were included in the study. 92 patients performed in the outer center of igneal biopsy, 2 patients placed with pathological diagnoses with transuretral resection material and 1 patient received hormone therapy before radical prostatectomy with 1 patient received radiotherapy was dismissed. The average age of the total of 71 patients involved in the study was 62.3 ± 6.0 (December, 46 - 75) years, while the pre-diagnostic average PSA level was 10.0 ± 7.6 (December, 3.2 - 48.1) ng/mL. 31 (43.7%) of the patients had suspicious findings in the finger rectal examination. The Gleason score between injustice biopsy samples and radical prostatectomy samples was 66.2, 59.2 and 74.6 per cent, respectively, in terms of prognostic group and tumor laterality. PROTECTION and RESULTS: In patients diagnosed with prostate cancer, the pathological assessment of injective biopsy samples plays a critical role in the determination of methods of treatment. However, it should be remembered that samples of injective biopsy do not predict prostate pathology with a high harmony.

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Acta Oncologica Turcica

Field :   Sağlık Bilimleri

Journal Type :   Ulusal

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Acta Oncologica Turcica