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 Görüntüleme 32
Usefulness of the SYNTAX Score II to Predict In-Hospital and Long-Term Mortality in ST-Segment Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention
2022
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Şişli Etfal Hastanesi Tıp Bülteni
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Özet:

Objectives: The prognostic significance of SYNTAX Score II (SS-II) is well-known in patients with chronic coronary syndromes. However, its predictive ability for mortality in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (p-PCI) remains unclear. Therefore, we aimed to investigate the prognostic accuracy of SS-II in STEMI patients who underwent p-PCI. Methods: A total of 743 STEMI patients treated with p-PCI were retrospectively analyzed. Study population was divided into three groups according to SS-II and defined as SS-IILOW ≤22.5 (n=245), 22.5 31 (n=255). In-hospital and long-term mortality at long-term follow-up were defined as clinical endpoints of the study. Results: The incidence of in-hospital (15% vs. 0.4% vs. 0.8%, p<0.001) and all-cause mortality (32.2% vs. 6.6% vs. 2.9%, p<0.001) were significantly higher in SS-IIHIGH group compared with the other two groups. In addition, Kaplan–Meier analysis showed statistically significantly increased incidence of death in SS-II > 31 group (P [log-rank] <0.001). SS-II >31 was defined as an independent predictor of all-cause mortality (hazard ratio 5.22 95% confidence interval 2.11–12.87 p<0.001). Area under the curve values derived from ROC analysis to evaluate the predictive accuracy of SS-II, anatomical and clinical SS, modified ACEF score, and Global Registry of Acute Coronary Events risk scores for all-cause mortality were 0.82, 0.71, 0.81, 0.82, and 0.82, respectively (p<0.001). Conclusion: SS-II has an increased predictive ability for in-hospital and long-term mortality in STEMI patients undergoing p-PCI.

Anahtar Kelimeler:

ST segment increased myocardial infarction due to primary percutaneous coronary initiative in patients applied to predict hospitalized and long-term mortality in the SYNTAX II score
2022
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Özet:

The prognostic importance of the SYNTAX II score (SS-II) is well known in patients with chronic coronary syndrome. However, primary percutaneous coronary initiative (PKG) applied ST-segment preserves uncertainty in the ability to predict mortality in patients with increased myocardial infarction (STYMI). Therefore, we aimed at investigating the prognostic accuracy of SS-II in STYMI patients with primary PKG. Methods: 743 STYME patients treated with Primary PKG were retroactively analyzed. The work population was divided into three groups according to SS-II and was defined as SS-IIDUCH ≤ 22.5 (n = 245), 22.5 < SS-IIORTA ≤ 31 (n = 243) and SS-IIHYCH > 31 (n = 255). Hospital and long-term mortality were defined as clinical conclusions of the study. Results: Hospital mortality (%15 -%0.4 -%0.8, p<0,001) and all causes-related deaths during follow-up (%32.2 -%6.6 - 2,%9, p<0,001) were significantly higher in the SS-IIHIGH group, compared to the other two groups. Also, the Kaplan-Meier analysis showed that the SS-II > 31 group had a significantly higher mortality incidence (p [log-rank] < 0.001). SS-II > 31 was defined as an independent predictor of all causes-related mortality (Hazard ratio 5.22% 95% confidence range 2.11-12.87 p<0,001). For all causes-related deaths, SS-II, anatomical and logistical clinical SS, modified age-creatine-injection fraction score (ACEF) and the remaining field values under the curve obtained from the ROC analysis of GRACE scores were 0.82, 0.71, 0.81, 0.82 and 0.82 respectively. (p < 0,001) Result: SS-II has an increased predictive ability for hospitalized and long-term mortality in p-PKG-applicated STYME patients. (SETB-2021-11-322)

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2022
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