Abstract:

Hypothyroidism has diverse effects on the liver, which may manifest themselves in various clinical forms from incidentally elevated liver function tests to ascites. Cholestasis is generally seen in hyperthyroidism and, in rare cases, along with hypothyroidism. We present a case who was referred to us for endoscopic retrograde cholangiopancreatography due to cholestasis. Intrahepatic cholestasis was revealed during follow-up and improved with treatment for hypothyroidism. We rarely encounter severely elevated serum bilirubin levels in patients with hypothyroidism in the literature. In patients with severe hypothyroidism, mild to moderate abnormal liver tests and elevated bilirubin may be seen, but our case had very high bilirubin levels compared with previously presented patients.

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