Özet:

Obesity is one of the major lifestyle disorders prevalent worldwide. The increasing obesity rate is associated with the emergence of diseases like thyroid dysfunction, dyslipidaemia, hormonal imbalance, etc. Obesity is the risk factor for heart disease, atherosclerosis, insulin resistance, arthritis, musculoskeletal disorders, and cancer. The present article portrays insights into the association of obesity with dyslipidemia, diabetes, hormonal imbalance, and hypothyroidism. Excessive or insufficient release of hormones can lead to obesity as leptin, insulin, sex hormones, and growth hormones influence appetite, metabolism, and body fat distribution. The article provides a review of the interrelationship of metabolic dysregulation with obesity and the further development of related diseases. This paper also summarizes the effects of dietary fibers and fish protein on metabolic alterations, hormonal imbalance, and hyperlipidemia associated with obesity. This article elaborated the role of dietary intervention like fiber and dietary protein consumption useful for managing obesity-related disorders. Potential nutraceutical products are consumed as frequent food sources. Still, quality human clinical trial data are lacking, signifying the need for substantial scientific work to assess the safety and efficacy of nutraceuticals.

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