Özet :

Two Sideritis species afforded eleven kaurene and one beyerene diterpenes. Structures of the compounds from Sideritis sipylea} were elucidated as linearol (1), 7-epicandicandiol (2), sideridiol (3), siderol (4), isolinearol (5), isosidol (6) and epoxyisolinearol (7). Linearol was treated with m -chloroperbenzoic to afford its analogues ent-3b ,7a ,17-trihydroxy-18-acetoxykaur-15-ene (1a) and ent}-7a ,17,18-trihydroxy-3b -acetoxykaur-15-ene (1b) as new compounds. From the second species, Sideritis dichotoma, the kaurenes sideridiol (3) siderol (4), ent-7a ,18-dihydroxy-15b ,16b -epoxykaurane (8)}, ent}-7a -acetoxy,18-hydroxy-15b ,16b -epoxykaurane (9), ent-7a -acetoxy-15,18-dihydroxy-kaur-16-ene (10), ent-7a ,15,18-trihydroxykaur-16-ene (11) and the beyerene ent-7a ,18-dihydroxybeyer-15-ene (12) were isolated. Structural elucidation is based on NMR techniques and mass spectrometer analyses.

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