Özet:

Abstract Background: Gout is an inflammatory disease characterized by acute arthritis attacks, which occurs as a result of the accumulation of monosodium urate crystals in the joints and tissues as a result of long-term hyperuricemia. In this study, demographic data and comorbid diseases of patients diagnosed with gout were investigated retro-spectively. Materials and Methods: This study was performed retrospectively in Kahramanmaraş Necip Fazıl City Hospital Rheumatology Clinic between January 2020 and December 2021. Patients over the age of 18 who were diag-nosed with gout according to the 2015 EULAR/ACR classification criteria were included in the study. Results: In totals, 110 patients who diagnosed gout were included, 77 of whom males (70%), 33 of whom fe-males (30%).The mean age of the patients was 60.3. The most common joint involvement was observed in the first metatarsal and in 89 patients (80.9%). The most common comorbidity in patients with gout was Diabetes mellitus and evaluated in 77 patients (70%). The other comorbidities, Hypertension in 59 patients (53.6%), Chronic renal failure in 49 patients (44.5%), Hyperlipidemia in 42 patients (38.2%), coronary artery disease in 35 patients (31.8%), Cerebrovascular events was observed in two patients (1.8%). Mean laboratory parameters are as falloows: wbc: 8268, Hgb: 14.17 g / dl, uric acid: 7.79 mg / dl, sedimentation: 19.7 mm / hour, CRP: 8.5 mg / l, Urea: 41 mg / dl, creatinine :1.2mg/dl . As medical treatment, colchicine was used in 80 patients (72.7%), allopu-rinol was used in 104 patients (94.5%), and febuxostat was used in two patients (1.8%). The uric acid level was observed to be within the target value in 30 patients (27.3%) and not at the target value in 80 patients (72.7%). Conclusions: In this study, demographic data, comorbid diseases and medical treatment responses of gout pa-tients were evaluated. These findings were found to be compatible with the literature. Diabetes mellitus, Hyper-tension, Coronary artery disease, Chronic renal failure, Obesity and diet are the main risk factors for the disease. Metabolic diseases should also be considered in the treatment of gout. Keywords: Gout, Arthritis, Comorbidity