Abstract:

OBJECTIVE: Neuro-Behcet's Syndrome (NBS), occurs due to central nervous system involvement of Behcet's disease (BD), and it is one of the factors that increase mortality and morbidity. In this study, we aimed to investigate the clinical, demographic and radiological data of Neuro-Behcet patients living in our region. MATERIAL AND METHODS: In this study, the records of 14 patients who were followed up with the diagnosis of NBS at Atatürk University Neurology Clinic between January 2015 and January 2019 were reviewed retrospectively. Analyses were made by using SPSS 20 statistical program. RESULTS: The ages of patients were between 18 and 45 years. The average age was 32,07+9,06 years, and NBS onset age was 29,9+6,8 years. % 35,7 (n=5) of patients with NBS were female, and % 64,3 (n=9) of them were male. The most common reason for admission was headache with % 57,1. % 50 of the patients with NBS in magnetic resonance imaging had parenchymal, and 50% of the patients had nonparenchymal involvement. One patient had coexistence of NBS and multiple sclerosis while one patient had an acute infarct area with diffusion restriction in the brain stem. In our study, mortality rate in NBS was % 7,1 (n=1). % 35,7 of the patients had a previously known diagnosis of BS, and % 64,3 (n=9) of them had been diagnosed BD with NBS diagnosis. The result of HLA-B51 was positive in 4 patients. CONCLUSIONS: The rate of patients with NBS and BD at the same time is significantly higher than the literature. It was thought that the effective factor was low sociocultural level. Early diagnosis and treatment are important factors that reduce the risk of developing NBS. Rarely coexistence of NBS and MS?.

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