Özet:

The coronavirus disease 2019 (COVID-19), which spread worldwide from the Chinese city of Wuhan at the end of December, was declared a pandemic by the World Health Organization on 11 March 2020. The effect of SARS-CoV-2 is similar to known coronavirus, but it has been revealed that in the last 20 years, severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) and coronavirus can be fatal with the transition from animal to human. As it can be seen with relatively mild symptoms such as dry cough, throat pain, headache, discomfort and fever, it can lead to severe pneumonia and death, which can result in acute respiratory disorder syndrome (ARDS) especially in cases with advanced age group and comorbid diseases. In addition, it is noted that the disease is not always transmitted from individuals who have symptoms, and asymptomatic people are important in the spread of the disease. COVID-19 is easily transmitted and rapidly spread during close contact with the infected person through the drops and by contact with the contaminated surfaces. There is not yet any evidence-based, effective and reliable, specific treatment that can be used against the COVID-19 factor. At this point, it is important to illuminate the development of SARS-CoV-2 and COVID-19 infections. In this collection, information on the pathogenesis of the COVID-19 disease was reviewed.

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