Özet:

Purpose: The aim of this study was to evaluate increased aortic elasticity parameters and myocardial function in children with celiac disease (CD) and the effect of the subclinical myocardial damage on the elasticity parameters.  Materials and Methods: Fiftytwo children with CD and 60 healthy subjects were included in the study. Patients were divided into two groups according to IgA-tissue transglutaminase (IgA-tTG) antibody results. All children's cardiac functions were assessed by conventional echocardiography and tissue Doppler (TDI) imaging. Aortic strain, distensibilty and stiffness index (SI) were calculated by M-mode echocardiography.   Results: Isovolumetric contraction time and isovolumetric relaxation time values and myocardial performance index (Tei) evaluated for both ventricles by TDI were significantly higher in patients. Right ventricle Tei index value was the highest in the group of serum IgA-tTG antibody positive. Patient group exhibited significantly lower strain values and higher SI than the controls.  Conclusion: Our study showed that aortic elasticity parameters in children with subclinical CD are related to arterial pressure and may be used to determine increased prematurity atherosclerosis risk. These results suggest that serious cardiovascular complications can be predicted with echocardiographic follow-up especially in children with antibody-positive CD.  

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