Özet:

Background:This study aimed to compare the acute kidney injury AKI) development and mortality rates in patients with variant B.1.1.7 positive and negative SARS-CoV-2 infection. Material and Methods: 92 variant B.1.1.7 negative (group I) and 57 variant B.1.1.7 positive (group II) SARS-CoV-2 patients were included in the study. Demographic data, comorbidities, the number of intensive care unit hospitalization days, the need for an invasive mechanical ventilator, number of mechanical ventilator days, whether acute renal failure developed, the day of acute renal failure development, and treatment outcome were recorded for each patient. Results: Group II patients (17/57 -29.8%) developed acute kidney injury at a higher rate than group I patients (31/92 -33.7%) (p=0.04).. 46/92 (50%) patients in group I and 38/57 (66.7%) patients in group II received invasive mechanical ventilation support (p <0.05). The mortality rate of patients without AKI development was higher in group II [ 22/40 (55%)] than group I [19/61 (31.2%)] (p<0.05). Conclusion: It was determined that the development of acute kidney injury in patients with critical illness and variant B.1.1.7 infection followed was less than in the other patients. This result suggested that the increase in mortality in variant B.1.1.7 infection occurred independently of the development of acute kidney injury.