Abstract:

Objective: Our aim is to evaluate blood glucose regulation in patients with diabetes using the triglyceride glucose index and the triglyceride to high density lipoprotein (HDL) ratio. Materials and Methods: The data of our retrospective study were obtained from the database of our hospital. The study was conducted with 340 type 2 patients with diabetes. Demographic data of the patients, glucose, hemoglobin A1c (HbA1c), high density lipoproteine-cholesterol (HDL-C), triglyceride, alanine aminotransferase (ALT) and creatinine values were recorded. The value obtained from the study was evaluated with the SPSS 21 version program. Results: Of the participants, 202 were female and 138 were male. Patients were divided into groups according to the percentage of HbA1cs. In the group with HbA1c ≥7%, triglyceride/HDL value, triglyceride-glucose index, fasting glucose, diabetes age, triglyceride values were statistically significantly higher, while HDL cholesterol was lower. We found a significant correlation between Triglyceride/HDL value, triglyceride glucose index with both glucose and HbA1c. The cut-off value of triglyceride-glucose (TyG) was 9.38. Conclusion: TG/HDL and TyG index values are related with HbA1c. In particular, the TyG index, whose cut-off value determined between these two parameters, is a parameter that can be used to evaluate good glycemic control instead of HbA1c in cases where HbA1c cannot be measured.

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