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Amaç: Yumurta alerjisi olan çocuklara içerisinde yumurta proteini bulunan kızamık-kızamıkçık-kabakulak (KKK) aşısının doğrudan uygulanması önerilmesine rağmen hekimler genellikle çekince yaşamakta, bu durum hekim ve ailelerde sıkıntılara yol açmaktadır. Bu çalışmamızda, kliniğimizde yumurta alerjisi nedeniyle izlenen hastalarda, KKK aşısı sonrası aşı reaksiyon sıklığının değerlendirilmesi amaçlanmıştır. Yöntem: Kliniğimizde yumurta alerjisi tanısı ile izlenen hastaların Ocak 2019-Ocak 2020 tarihleri arasında KKK aşı kayıtları incelendi. KKK aşısı yapılan hastaların demografik ve klinik özellikleri, laboratuvar bulguları değerlendirildi. Bulgular: Tanı anında yaş ortalaması 6,1±2,7 ay olan 80 hastanın %62,5’i (n=50) erkek idi. Hastaların %68,8’inde (n=55) atopik dermatit, %18,8’inde (n=15) ürtiker- anjioödem, %25’inde (n=20) reaktif hava yolu hastalığı, %15’inde (n=12) anafilaksi, %16,3’ünde (n=13) proktokolit mevcuttu. Tüm hastalara KKK aşısı aşı ile test yapılmadan, tek dozda uygulandı. Bir hastada aşıdan 30 dakika sonra aşırı ağlama, huzursuzluk ve yüzde kızarıklık şeklinde reaksiyon gözlenirken antihistaminik sonrası 1 saat içinde şikayetleri geriledi. Diğer hastalarda izlemlerinde sorun yaşanmadı. Sonuç: Yumurta alerjili hastalarda KKK aşısı sonrası herhangi bir ciddi reaksiyon gözlenmemiştir. Bağışıklama ve yapılma zamanı önemli olması nedeniyle yumurta alerjisi olan hastalarda KKK aşısının güvenle yapılabileceğini düşünüyoruz. Ancak aşı yapılan merkezlerde olası reaksiyonlara müdahale edilebilir uygun koşullar sağlanmalı ve aşı sonrası hastalar uygun süre gözlem altında bulundurulmalıdır.
Objective: Despite the recommendation of the direct application of the bacterium-bacterium-bacterium vaccine (CCC) containing egg protein in children with an allergy to eggs, doctors often live in fear, which leads to trouble in doctors and families. In this study, in patients monitored due to egg allergy in our clinic, we aimed at assessing the frequency of vaccine reactions after vaccination. Method: Patients diagnosed with an egg allergy in our clinic have been examined KKK vaccine records between January 2019 and January 2020. The demographic and clinical characteristics of the patients who were vaccinated with CCC were evaluated, laboratory findings. Results: 62.5 per cent of 80 patients with an immediate age of 6.1±2.7 months (n=50) were male. In 68.8 percent of patients (n=55) atopic dermatitis, in 18.8 percent (n=15) urethral angioedema, in 25 percent (n=20) reactive airway disease, in 15 percent (n=12) anaphylaxis, in 16.3 percent (n=13) proctocolite. All patients were administered in a single dose, without having been tested with the KKK vaccine. A patient observed an excessive crying, anxiety, and a percentage of redness reaction 30 minutes after the vaccination, while the complaints fell within 1 hour after the antihistaminic treatment. There were no problems with other patients. Result: No serious reaction has been observed after vaccination in egg allergic patients. We believe that in patients with an egg allergy, KKK vaccine can be taken safely due to the importance of immunization and time of preparation. However, appropriate conditions should be provided in the vaccine centers that can interfere with possible reactions and the post-vaccination patients should be monitored for a reasonable time.
Objective: Although direct administration of the measles -mumps -rubella (MMR) vaccine which contains egg protein is recommended to children with egg allergy, physicians often have reservations, this situation leads to problems in physicians and families. In this study, we aimed to evaluate the frequency of reaction after the MMR vaccine in patients who were monitored for egg allergy in our clinic. Methods: MMR vaccination records were examined between January 2019 and January 2020 of patients diagnosed with egg allergy in our clinic. Demographic and clinical characteristics, laboratory findings were evaluated in patients vaccinated with MMR Results: The average age was 6.1±2.7 months, and 62.5% (n=50) of the cases were male. According to their diagnostic distribution, the patients had atopic dermatitis (n=55; 68.8%), urticaria (n=15; 18.8%), reactive airway disease (n=20; 25%), proctocolitis (n=13; 16.3%) and anaphylaxis (n=12; 15%). A whole dose of vaccine was administered to all cases. Flushing and crying was observed in one patient 30 minutes after vaccination, while her complaints resolved 1hour after antihistamine. No problems were observed in the follow-up of other patients. There was no severe side effect in any of the cases. Conclusion: No serious reactions have been observed in patients with egg allergy after the MMR vaccine. We believe that the MMR vaccine can be safely administered in patients with egg allergy in vaccinated centers, as immunization and delivery time are important. However, appropriate conditions can be intervened in possible reactions and patients should be kept under observation for the appropriate period after vaccination.
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
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