Amaç: Resveratrol (trans-3,5,4’-trihidroksi-stilben) üzüm, asma, yer fıstığı, kızılcık, yaban mersini gibi birçok bitkisel kaynakta bulunan polifenolik bir bileşiktir. Resveratrol ile ilgili daha önceki araştırmalar kardiyovasküler sistemler, inflamasyon ve karsinogenez/kanser gelişimi ile ilgili farmakolojik etkileri üzerine odaklıyken son zamanlarda araştırmaların büyük çoğunluğu yaşlanma süreci, diyabet, alzheimer ve diğer nörodejeneratif hastalıklar üzerinde potansiyel etkileri keşfedilerek genişletilmiştir. Bu derleme kapsamında resveratrol hakkında genel bilgilerin, bulunduğu kaynakların ve özellikle son yıllarda üzerinde çalışılan biyolojik etkilerinin (in vitro, in vivo) derlenmesi amaçlanmıştır.
Purpose: Resveratrol (trans-3,5,4'-trihydroxy-stilben) is a polyphenolic compound found in many plant sources, such as grapes, ashes, land beans, red, wild mercury. Previous research on resveratrol focuses on the pharmacological effects related to the cardiovascular systems, inflammation and carcinogenesis/cancer development, while the majority of recent research has been extended to discover potential effects on ageing process, diabetes, Alzheimer’s and other neurodegenerative diseases. This collection aims to aggregate the general information about resveratrol, the sources in which it is located and the biological effects (in vitro, in vivo) studied in recent years.
Objective: Resveratrol (trans-3,5,4'-trihydroxy-stilbene) is a polyphenolic compound found in many plant sources such as grapes, vine, peanuts, cranberries, blueberries. While previous research on resveratrol has focused on its pharmacological effects on cardiovascular systems, inflammation, and carcinogenesis/cancer development, most of the research has recently been expanded by exploring its potential effects on the aging process, diabetes, Alzheimer's, and other neurodegenerative diseases. Within the scope of this review, it is aimed to compile general information about resveratrol, its sources, and especially its biological effects (in vitro, in vivo) studied in recent years.
Alan : Sağlık Bilimleri
Dergi Türü : Uluslararası
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