Abstract:

In the Health Application and Research Hospital of Kahramanmaraş Sütçü Imam University, microorganisms and antibiotic sensitivities isolated from blood cultures are one of the leading causes of blood circulation infections, mortality and morbidity. The aim of our study is to identify the infectious factors and antibiotic sensitivities identified in blood cultures. Tools and Methods: 3719 isolates are included in the work. Blood culture samples are incubated with the BACT/ALERT 3D automated system. The identification and antibiotic sensitivity of the reproductive microorganisms are performed by the Phoenix automated system. The most commonly isolated Gram negative bacteria were found as Escherichia coli 227 (36.37%), Klebsiella pneumoniae 126 (20.19%). It was found that 2245 of the Gram-positive bacteria were coagulated negative Staphylococcus species, 251 (8.8%) Enterococcus spp., 194 (6.87) Staphylococcus aureus. Gram-negative bacteria-effective antibiotics have been found as carbapenems, aminoglycosides and tigesiclin. All Acinetobacter islands have been found resistant to carbapenems. In Staphylococcus aureus isolates, vancomycin resistance was not identified, while methylin resistance was 55% and methylin resistance was 84% in coagulase negative Staphylococcus isolates. The Enterococcus spp. In isolates, the vancomycin resistance was 9.7%. The result: As a result, the bacterial resistance rates are so high, it suggests that infection control measures should be increased. Keywords : Antibiotic resistance; blood culture; blood circulation infection; microorganism Microorganism isolated from blood culture and their antimicrobial susceptibilities obtained at The University Health Practice and Research Hospital ABSTRACT Objective: Blood stream infections remain a major cause of morbidity and mortality. The aim of this study is to determine the types of microorganisms and antibiotic susceptibility isolated from blood cultures. Materials and Methods: 3719 isolates identified included in the study. Blood culture samples were incubated in BACT/ALERT 3D automated system. Identification and antibiotic susceptibility of microorganisms were done with Phoenix automated system. Results: The most frequent Gram negative bacteria were Escherichia coli 227 (36.3%), Klebsiella pneumoniae 126 (20.1%). The most frequent Gram positive bacteria were 2245 (79.5%) coagulase negative Staphylococcus, 251 (8.8%) Enterococcus spp., 194 (6.87%) Staphylococcus aureus. Carbapenems, aminoglycosides and tigecycline were the most effective antibiotics against all Gram negatives. All Acinetobacter islands were resistant to carbapenems. No resistance to vancomycin was detected Staphylococcus aureus. Methicillin resistance was 55% to Staphylococcus aureus, 84% to coagulase negative Staphylococcus. Vancomycin resistance was 9.7% to Enterococcus spp.. Conclusion: As a result, the high resistance rates of bacteria suggest that infection control measures should be increased. Key words : Antibiotic resistance; blood culture; blood stream infection; microorganism

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