The fruits, aerial parts and roots of Neomuretia pisidica (Kit Tan) Kljuykov, Degtjareva & Zakharova were extracted with n-hexane. Total of 18 compounds were characterised by GC analyses of the n-hexane extracts. Main volatile components of the n-hexane extract of aerial parts were characterized as 1,8-cineole (23.4 %), camphor (21.4 %), 2-ethyl hexanol (14.6 %), α-pinene (7.2 %), and verbenone (6.4 %). Methyl linoleate (19.3 %), 1,8-cineole (16.5 %), camphor (13.2 %), α-pinene (6.1 %) and 2-ethyl hexanol (4.9 %) were found in the n-hexane extract of roots. Whereas, 1,8-cineole (23.3 %), camphor (20.3 %), 2-ethyl hexanol (14.2 %), α-pinene (9.9 %), and limonene (4.1%) were the major components of the n-hexane extract of fruits. Antimicrobial activity were identified using a microdilution assay against selected human pathogenic strains. The most potent inhibitor activities with 156 µg/mL concentrations were detected against S. aureus and E. faecalis.