Abstract:

Acinic cell carcinoma (ACC) of the breast is extremely rare, similar to a comparable tumor occurring in the salivary glands and is characterized with favorable prognosis. Presented patient was a 53-year-old woman, who noticed a mass in the right breast. A tru-cut biopsy was performed, and histological diagnosis was reported as invasive ductal carcinoma. Because of disproportion between tumor and breast volume, neodjuvant chemotherapy was performed. Subsequently wide excision and sentinel lymph node biopsy was performed. Histologically tumor showed diffuse glandular infiltrative pattern with small aciner structures. Immunohistochemically tumor was ER(+), PR (-), CerbB2 (-) and alfa-1 antitrypsin (+) and diagnosed as primary acinic cell carcinoma of breast. In the postoperative period radiation and adjuvant hormone treatment was performed. The patient was alive and free of recurrence or metastasis after 1 year follow up.

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